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Microalgae and microbial inoculant as partial substitutes for chemical fertilizer enhance yield and quality by improving soil microorganisms.
Front Plant Sci
January 2025
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Excessive utilization of chemical fertilizers degrades the quality of medicinal plants and soil. Bio-organic fertilizers (BOFs) including microbial inoculants and microalgae have garnered considerable attention as potential substitutes for chemical fertilizer to enhance yield. In this study, a field experiment was conducted to investigate the effects of BOF partially substituting chemical fertilizer on the growth and quality of medicinal plant .
View Article and Find Full Text PDFImaging of biphasic signalosomes constructed by checkpoint receptor 2B4 in conventional and chimeric antigen receptor-T cells.
iScience
January 2025
Department of Immunology, Tokyo Medical University, Tokyo 160-8402, Japan.
A co-signaling receptor, 2B4, has dual effects in immune cells, but its actual functions in T cells remain elusive. Here, using super-resolution imaging technology with an immunological synapse model, we showed that 2B4 forms "2B4 microclusters" immediately after 2B4-CD48 binding. A lipid phosphatase, SHIP-1, subsequently combined with 2B4 to form coinhibitory signalosomes, leading to the suppression of cytokine production.
View Article and Find Full Text PDFRespiratory metrics of neonatal positive pressure ventilation on different ventilatory rates: A simulation study.
Resusc Plus
January 2025
Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Background: Effective ventilation is the core of neonatal resuscitation (NR). T-piece resuscitators (TPR) and self-inflating bags (SIB) are the two most widely utilized resuscitation devices. Nevertheless, limited information is available regarding the respiratory metrics during NR with these devices.
View Article and Find Full Text PDFFluorine-Free Nanofiber/Network Membranes with Interconnected Tortuous Channels for High-Performance Liquid-Repellency and Breathability.
ACS Nano
January 2025
Innovation Center for Textile Science and Technology, College of Textiles, Donghua University, Shanghai 200051, China.
The excessive use of fluoride in fibrous membranes poses significant bioaccumulative threats to the environment and human health. However, most existing membranes used in protective clothing and desalination systems show high fluorine dependence and inevitable trade-offs between liquid repellency and breathability. Herein, fluorine-free bonded scaffolded nanofiber/network membranes are developed using the electro-coating-netting technique to achieve high-performance liquid-repellency and breathability.
View Article and Find Full Text PDFProbiotic active gel promotes diabetic wound healing through continuous local glucose consumption and antioxidant.
J Nanobiotechnology
January 2025
Shandong Key Laboratory of Proteins and Peptides Pharmaceutical Engineering, Shandong Universities Key Laboratory of Biological Medicine, School of Life Science and Technology, Shandong Second Medical University, 7166 # Baotong West Street, Weifang, Shandong, 261053, People's Republic of China.
Background: Diabetic foot ulcers (DFU) are severe complications of diabetes, posing significant health and societal challenges. Accumulation of reactive oxygen species (ROS) and elevated glucose levels are primary factors affecting diabetic wound healing. Achieving effective treatment by reducing ROS alone is challenging, as high glucose levels continuously drive ROS production.
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