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Characterizing Schizophrenia Spectrum Disorders: Results of the U.S. Mental and Substance Use Disorders Prevalence Study.
Psychiatr Serv
January 2025
Department of Psychiatry, Columbia University Irving Medical Center, and New York State Psychiatric Institute, New York City (Bareis, Dixon, Olfson, Smith, Stroup); RTI International, Research Triangle Park, North Carolina (Edlund, Ringeisen, Guyer, Geiger); Department of Epidemiology, Mailman School of Public Health, Columbia University, New York City (Olfson, Kreski); Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle (Chwastiak, Monroe-DeVita), School of Medicine and the Wilson Center for Science and Justice, School of Law, Duke University, Durham, North Carolina (Swartz, Swanson); National Association of State Mental Health Program Directors, Washington, D.C. (Sinclair Hancq).
Objective: Current information on treatment and clinical characteristics of U.S. adults with schizophrenia spectrum disorders (i.
View Article and Find Full Text PDFDiagnostic shift in adolescents with first episode psychosis: findings from the 2-year follow-up of the "Parma Early Psychosis" program.
Soc Psychiatry Psychiatr Epidemiol
June 2024
Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum Università di Bologna, viale Pepoli 5, Bologna (BO), 40123, Italy.
Purpose: Diagnostic stability for people with First Episode Psychosis (FEP) is essential for treatment, but it remains poorly investigated, especially in adolescents and within a prospective design. The aims of this research were: (a) to examine diagnostic change in Italian adolescents with FEP treated within an "Early Intervention in Psychosis" program during a 2-year follow-up period and (b) to investigate any sociodemographic and clinical predictors at baseline.
Methods: At baseline, 66 adolescents with FEP was recruited.
Sensory ataxic polyneuropathy unmasking late-onset urea cycle defect.
Clin Neurol Neurosurg
May 2024
Department of Neurology, All India Institute of Medical Sciences, Jodhpur, India. Electronic address:
Article Synopsis
- A 63-year-old man with type 2 diabetes and a history of hepatic encephalopathy presented with lower limb weakness, sensory issues, and mood swings, alongside a family history of mental disorders.
- Nerve conduction studies revealed demyelinating polyradiculoneuropathy, while MRI indicated thickened cranial and lumbosacral nerves; he was initially treated for chronic inflammatory polyneuropathy.
- After developing encephalopathy and an elevated serum ammonia level, further tests pointed to ornithine transcarbamylase (OTC) deficiency, leading to successful treatment with hemodialysis and dietary changes.
Diagnostic shift in first episode psychosis: Results from the 2-year follow-up of the "Parma Early Psychosis" program.
Schizophr Res
May 2024
Department of Biomedical and Neuromotor Sciences, "Alma Mater Studiorum" Università di Bologna, Bologna, BO, Italy.
Purpose: Although the stability of current diagnostic criteria for people with First Episode Psychosis (FEP) is essential for treatment, it still remains poorly investigated. As its examination necessarily requires a prospective evaluation of diagnostic trajectories, the aims of the current longitudinal investigation were: (a) to assess diagnostic changes in an Italian FEP population treated within an "Early Intervention in Psychosis" service during a 2-year follow-up period, and (b) to identify potential sociodemographic and clinical moderators of diagnostic instability at entry.
Methods: All participants were FEP individuals, aged 12-35 years.
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