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http://dx.doi.org/10.1111/j.1439-0507.1982.tb01919.x | DOI Listing |
Acta Derm Venereol
August 1992
Department of Dermatology, University of Minnesota Medical School, Minneapolis.
Trichophyton rubrum infects skin. This fungus or its products might affect the function of epidermal cells. We previously reported that T.
View Article and Find Full Text PDFDrugs Exp Clin Res
February 1990
Central Research Laboratories, Meiji Seika Kaisha, Ltd., Yokohama, Japan.
2-(2,3,3-Triiodoallyl)tetrazole (ME1401), a novel antifungal agent, showed therapeutic effectiveness in topical treatment of experimental dermal infections with Trichophyton mentagrophytes and Candida albicans in guinea-pigs. Addition of diethyl sebacate to the ME1401 preparations increased its in vivo antifungal activity and its penetration into the skin. When the estimation of efficacy of treatment with active formulations was made on the basis of skin lesion and the rate of negative skin cultures in comparison with those for infected, untreated or placebo-treated controls, the in vivo activity of 0.
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