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Evaluation of the Feasibility of Transfusing Leukocyte Depletion Filter-Processed Intraoperative Cell Salvage Blood in Metastatic Spine Tumor Surgery: Protocol for a Non-Randomized Study.
JMIR Res Protoc
January 2025
Department of Orthopaedic Surgery, National University Hospital, National University Health System, Singapore, Singapore.
Background: Metastatic spine tumor surgery (MSTS) is often complex and extensive leading to significant blood loss. Allogeneic blood transfusion (ABT) is the mainstay of blood replenishment but with immune-mediated postoperative complications. Alternative blood management techniques (salvaged blood transfusion [SBT]) allow us to overcome such complications.
View Article and Find Full Text PDFBackground: Pelvic fractures often result in traumatic and intraoperative blood loss. Cell salvage (CS) is a tool where autologous blood lost during surgery is collected and recycled with anticoagulation, centrifugation to separate red blood cells, and washing to be reinfused back to the patient. The purpose of this study was to investigate our experience with CS in pelvic and acetabular surgery and its relationship to perioperative transfusion requirements.
View Article and Find Full Text PDF[Decolonization of autologous blood with cefuroxime during hardware reinfusion in neurosurgical patients].
Zh Vopr Neirokhir Im N N Burdenko
December 2024
Burdenko Neurosurgical Center, Moscow, Russia.
Article Synopsis
- Autologous blood obtained during surgical hardware reinfusion is often contaminated with bacteria, predominantly from skin microflora, in up to 90% of cases, posing a risk for infection.
- Adding cefuroxime to the blood collection process was found to eliminate bacterial growth in 100% of instances when administered initially.
- Despite various decontamination methods, including washing and leukocyte filtration, some bacterial contamination remained, though the combination of these techniques with cefuroxime significantly reduced the risk of bacterial presence in processed blood samples.
RECENT TRENDS IN THE USE OF CELL SALVAGER FOR ORTHOPAEDIC TRAUMA AND ELECTIVE SURGERIES-A NARRATIVE REVIEW.
Georgian Med News
September 2024
University Hospitals Sussex NHS Foundation Trust, United Kingdom.
Intraoperative blood loss management is a critical concern in orthopaedic surgeries, particularly in trauma and complex elective procedures. Traditionally, allogeneic blood transfusions have been used to manage significant blood loss, but they carry risks such as transfusion reactions, infections, and increased healthcare costs. Cell salvage, or autotransfusion, offers a safer alternative by collecting, processing, and reinfusing the patient's own blood during surgery.
View Article and Find Full Text PDFPredeposit Autologous Blood Donation in Rh(D)-Negative Pregnant Women: A Single-Center Study.
AJP Rep
July 2024
Department of Blood Transfusion, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.
The primary purpose of this study was to assess the practicability of predeposit autologous blood donation (PABD) in the practice of Rh(D)-negative pregnant women. A cohort of 405 Rh(D)-negative pregnant women who had a delivery in the comprehensive tertiary hospital in Nanjing was analyzed retrospectively, over 10 years. After PABD, 203 women experienced a slight drop in mean hemoglobin of 5.
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