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The Spatial Ventricular Gradient Is Associated with Pacing-Induced Cardiomyopathy.
Heart Rhythm
December 2024
Harvard-Thorndike Electrophysiology Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA. Electronic address:
Background: Pacing-induced cardiomyopathy (PICM) is a frequent complication of right ventricular pacing that often requires re-operation for biventricular or conduction system pacing. Better methods for predicting PICM may inform initial pacing strategy and follow-up monitoring.
Objective: To determine if the spatial ventricular gradient (SVG), a vectorcardiographic marker of ventricular electrical and mechanical heterogeneity, is associated with subsequent development of PICM.
Evaluation of electrocardiographic criteria for predicting left ventricular hypertrophy and dilation in presence of left bundle branch block.
J Electrocardiol
December 2024
Department of Cardiovascular Medicine, The University of Kansas Medical Center, Kansas City, KS, United States of America. Electronic address:
Article Synopsis
- The study investigates the effectiveness of standard ECG criteria for diagnosing left ventricular hypertrophy (LVH) in patients with left bundle branch block (LBBB) and finds that QRS duration is a more reliable indicator than traditional criteria.
- Researchers included 413 adults with LBBB and compared the predictive power of QRS duration to established LVH criteria by assessing LV mass and volume through echocardiograms.
- Results showed that QRS duration had higher diagnostic accuracy for LVH and dilation in both men and women compared to any other ECG criteria, establishing it as a better predictor in these patients.
Unsupervised denoising of the non-invasive fetal electrocardiogram with sparse domain Kalman filtering and vectorcardiographic loop alignment.
Physiol Meas
July 2024
Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands.
Even though the electrocardiogram (ECG) has potential to be used as a monitoring or diagnostic tool for fetuses, the use of non-invasive fetal ECG is complicated by relatively high amounts of noise and fetal movement during the measurement. Moreover, machine learning-based solutions to this problem struggle with the lack of clean reference data, which is difficult to obtain. To solve these problems, this work aims to incorporate fetal rotation correction with ECG denoising into a single unsupervised end-to-end trainable method.
View Article and Find Full Text PDFCoronary Artery Occlusion Detection Using 3-Lead ECG System Suitable for Credit Card-Size Personal Device Integration.
JACC Adv
August 2023
Department of Medicine, Clinical Center of Serbia, Belgrade, Serbia.
Background: Early coronary occlusion detection by portable personal device with limited number of electrocardiographic (ECG) leads might shorten symptom-to-balloon time in acute coronary syndromes.
Objectives: The purpose of this study was to compare the accuracy of coronary occlusion detection using vectorcardgiographic analysis of a near-orthogonal 3-lead ECG configuration suitable for credit card-size personal device integration with automated and human 12 lead ECG interpretation.
Methods: The 12-lead ECGs with 3 additional leads ("abc") using 2 arm and 2 left parasternal electrodes were recorded in 66 patients undergoing percutaneous coronary intervention prior to ("baseline", n = 66), immediately before ("preinflation", n = 66), and after 90-second balloon coronary occlusion ("inflation", n = 120).
The spatial ventricular gradient is associated with inducibility of ventricular arrhythmias during electrophysiology study.
Heart Rhythm
November 2024
Harvard-Thorndike Arrhythmia Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts. Electronic address:
Background: Myocardial electrical heterogeneity is critical for normal cardiac electromechanical function, but abnormal or excessive electrical heterogeneity is proarrhythmic. The spatial ventricular gradient (SVG), a vectorcardiographic measure of electrical heterogeneity, has been associated with arrhythmic events during long-term follow-up, but its relationship with short-term inducibility of ventricular arrhythmias (VAs) is unclear.
Objective: This study was designed to determine associations between SVG and inducible VAs during electrophysiology study.
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