The effect of the antioxidant Ronoxan A and of two of its components (ascorbyl palmitate, lecithin) and of tocopheryl acetate was tested for the stabilization of fats and retinyl acetate. In the present study, results obtained in sunflower oil, soybean oil, milk fat and in the mixtures of these fats in concentrations corresponding to their levels in the Czechoslovak Infant Formula (Feminar) are compiled. The antioxidant levels applied, i.e. those used in Czechoslovakia for the stabilization and enrichment of vegetable oils and Feminar, have a protective effect on retinyl acetate to a certain extent as well, and in no case they affect it unfavourably. All antioxidant combinations applied cause a significant retardation of the fat autoxidation. Ronoxan A has the best effect in all cases tested.
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Curr Dev Nutr
November 2024
Institute for Global Nutrition and Department of Nutrition, University of California, Davis, Davis, CA, United States.
Background: Limited data are available on vitamin A kinetics and total body stores (TBS) in women. Such information can be obtained using compartmental modeling and retinol isotope dilution (RID).
Objectives: Objectives were to apply population-based ("super-subject") modeling to determine retinol kinetics in nonpregnant Ghanaian women of reproductive age and to use RID to predict TBS in the group and its individuals.
Nat Biotechnol
September 2024
Murdoch Children's Research Institute, The Royal Children's Hospital, Parkville, Victoria, Australia.
Hematopoietic stem cells (HSCs) derived from human induced pluripotent stem cells (iPS cells) have important biomedical applications. We identified differentiation conditions that generate HSCs defined by robust long-term multilineage engraftment in immune-deficient NOD,B6.Prkdc Il2rg Kit mice.
View Article and Find Full Text PDFBiomacromolecules
June 2024
College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310014, Zhejiang, China.
This study utilizes mechanochemistry to prepare retinol acetate (RA) solid dispersion (RA-sodium starch octenyl succinate (SSOS)), resulting in improved solubility, stability, and bioavailability compared with raw RA and commercial RA microcapsules. RA, poloxamer 188, SSOS, and milling beads (8 mm) were mixed in a ratio of 2:1:8:220 (w/w) and ball-milled at 100 rpm for 3 h. RA-SSOS exhibited a solubility of 1020.
View Article and Find Full Text PDFFood Chem
August 2024
Hubei Hongshan Laboratory, National Research and Development Centre for Egg Processing, College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, PR China. Electronic address:
This work presents a novel use of fibrous egg white protein (FEWP) in food preservation and nutraceutical applications. In this study, food-grade FEWP was used as an encapsulating material, along with chitosan (CS), to stabilize emulsions. The emulsion system was then used as a delivery system to improve the stability of retinyl acetate (RA).
View Article and Find Full Text PDFJ Chromatogr A
March 2024
Department of Analytical and Material Science, BASF SE, Carl-Bosch-Straße 38, Ludwigshafen am Rhein 67056, Germany. Electronic address:
The separation of vitamin A acetate isomers is essential for quality assurance of e.g. nutrition supplements, cosmetics, and pharmaceutical ingredients.
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