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Objectives: Central nervous system complications of acute pancreatitis (AP) can result in cerebral edema (CE). We assessed the risk of serious outcomes and health care features associated with CE in patients hospitalized with AP.

Methods: We conducted a retrospective cohort study using the National Inpatient Sample database.

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Variations in cerebral blood flow and blood volume interact with intracranial pressure and cerebrospinal fluid dynamics, all of which play a crucial role in brain homeostasis. A key physiological modulator is respiration, but its impact on cerebral blood flow and volume has not been thoroughly investigated. Here we used 4D flow MRI in a population-based sample of 65 participants (mean age = 75 ± 1) to quantify these effects.

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Objectives: The pulse pressure (PP) is an important factor influencing the outcomes of diabetes. However, the relationship between the PP and prediabetes has been rarely studied and how this association might be impacted by hypertension is not clear.

Methods: In this study, we retrospectively included 184,252 adults from 32 regions in China, spanning from 2010 to 2016.

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Genetic influence on choroidal vascularity index.

PLoS One

January 2025

Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Purpose: To investigate the heritability of genetic influence on macular choroidal vascularity index (CVI).

Methods: Total choroidal area (TCA), luminal area (LA), and CVI was measured using horizontal scan of spectral-domain optical coherence tomography with enhanced depth imaging in the 373 healthy twin participants. Characteristics of the participants were investigated, including age, sex, axial length, hypertension, diabetes, drinking habits, and smoking status.

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Video-based estimation of blood pressure.

PLoS One

January 2025

Department of Mechanical Engineering, Carnegie Mellon University, Pittsburgh, PA, United States of America.

In this work, we propose a non-contact video-based approach that estimates an individual's blood pressure. The estimation of blood pressure is critical for monitoring hypertension and cardiovascular diseases such as coronary artery disease or stroke. Estimation of blood pressure is typically achieved using contact-based devices which apply pressure on the arm through a cuff.

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