Surgical desympathization of skeletal muscle fibre does not change the resting membrane potential or input resistance of muscle fibre membrane, but induces extrajunctional sensitivity to acetylcholine though lesser by half than that after anatomical muscle denervation. Raucedil injection and nerve stump transplantation on the muscle do not cause any changes in muscle membrane. The data obtained suggest the sympathetic nervous system participation in neurotropic control of muscle membrane sensitivity to acetylcholine.
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