Cerebral gumma.

J Assoc Physicians India

Published: May 1982

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Case report: Cerebral syphilitic gumma: a case retrospective report of eight cases.

Front Med (Lausanne)

November 2024

Department of Neurosurgery, The Ganzhou Affiliated Hospital, Jiangxi Medical College, Nanchang University, Ganzhou, Jiangxi, China.

Background: Cerebral syphilitic gumma (CSG), a rare manifestation of neurosyphilis, presents characteristics akin to intracranial tumors, often leading to clinical misdiagnosis.

Objective: This study aimed to summarize the clinical experience in diagnosing and treating CSG.

Materials And Methods: The present study conducted a retrospective analysis of clinical data, encompassing the baseline characteristics, clinical presentation, diagnosis, treatment, and prognosis of eight patients with CSG who were treated and diagnosed by our institution.

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Contribution of advanced neuroimaging in diagnosis of cerebral syphilitic gumma: a case report.

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Department of Radiology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, China.

Article Synopsis
  • Cerebral syphilitic gumma is a rare infection in the brain that is difficult to diagnose without a known history of syphilis or thorough blood tests, as traditional MRI scans may not provide clear indications.
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Cerebral syphilitic gumma misdiagnosed as brain abscess: A case report.

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Department of Neurosurgery, Shengli Oilfield Central Hospital, Dongying 257099, Shandong Province, China.

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  • Cerebral syphilitic gumma is a rare condition often mistaken for brain tumors or abscesses due to its non-specific symptoms and similar imaging results.
  • A reported case involved a patient initially misdiagnosed with a brain abscess, leading to unnecessary surgery until a correct diagnosis of syphilitic gumma was made post-operation.
  • To improve diagnostic accuracy, it’s crucial for physicians to recognize the characteristics of neurosyphilis and combine multiple examination methods in their assessments.
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Moyamoya disease (MMD) is a rare idiopathic progressive vaso-occlusive disease characterized by irreversible vascular occlusion and collateral development of distal internal carotid arteries. Initially perceived as an exclusive entity to the East Asian population, the disease is now being reported globally, affecting individuals of diverse ethnicities. We present a case of a 55-year-old African American male patient with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) and a prior history of cryptococcal meningitis presenting to the emergency department with recurrent episodic headaches, which was refractory to routine medical therapy.

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