AI Article Synopsis
- The study investigated amino acid absorption in rats post-gastrectomy using 15N-glycine.
- 29 rats were divided into groups: 10 operated by Graham, 9 by Longmire and 12 controls, with measurements of 15N excretion taken every 12 hours.
- Despite differences in nitrogen excretion among the operated groups, all rats maintained a positive nitrogen balance and normal protein synthesis rates, indicating that the absorption issues were not critical.
Article Abstract
The investigations were carried out in rats by means of the amino acid 15N-glycinee 6 to 12 weeks after the gastrectomy. 10 rats were operated by Graham and 9 by Longmire, Gütgemann. 12 rats as a control group were not operated. The animals got a single dose 15N-glycin with the food in the beginning of the experiment. The excretion of the isotope was measured every twelve hours for 5 days. All rats had a positive nitrogen balance. The rats operated by Graham excreted with the urine significantly less 15N than the rats of the other two groups. These differences were caused by different fast adsorption of the amino acids likely, at this the rats operated by Graham absorbed retardingly evident qualified by the absent duodenal passage. These disturbances of the amino acid absorption are not aggravating, because the nitrogen balance and the protein synthesis rate of the animals were normal.
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