378 cases of isolated hypereosinophilia (eosinophils greater than 500 by mm3 of blood) are presented. The diagnosis was done for 189 cases: 184 parasitic diseases and 5 non parasitic diagnosis (3 neoplastic syndromes). The diagnosis was done more often if patients came back from a tropical area, if hypereosinophilia was observed on two samples of blood, if hypereosinophilia was major (greater than 2,500 eosinophils). The diagnosis was not done for 189 cases, but 49 patients have had an allergic disease. Drug etiologies are certainly underestimated.

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