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Placental ischemia during pregnancy induces hypertension, cerebral inflammation, and oxidative stress in dams postpartum.
Hypertens Pregnancy
December 2025
Department of Physiology and Anatomy, University of North Texas Health Science Center, Fort Worth, TX, USA.
Background: Preeclampsia (PE) is characterized as de novo hypertension (HTN) with end-organ damage, especially in the brain. PE is hypothesized to be caused by placental ischemia. PE affects ~5-8% of USA pregnancies and increases the risk for HTN and cerebrovascular diseases (CVD) later in life.
View Article and Find Full Text PDFPedicle Screw Placement in Pediatric and Adolescent Spinal Deformity Surgery: Does Tapping of the Pedicle Screw Tract Increase Safety?
J Pediatr Orthop
January 2025
Department of Orthopaedics, Division of Pediatrics and Adolescent Orthopaedic Surgery and Division of Spine Surgery, Washington University School of Medicine, St. Louis, MO.
Introduction: Since the development of pedicle screw fixation in the spine, safe placement has remained a crucial component in maximizing patient outcomes and mitigating pedicle screw-related complications. The purpose of this study is to investigate the utility of pedicle tapping in identifying pedicle breaches.
Methods: A pediatric spine surgery database was queried to identify a consecutive series of patients who underwent spinal deformity surgery utilizing pedicle screw fixation between May 2019 and October 2022.
Clomipramine-Induced Urinary Retention in an Adult Male - A Case Report.
Curr Drug Saf
January 2025
Department of Pharmacology, Government Medical College, Bhavnagar, India.
Background: Clomipramine, a Tricyclic Antidepressant (TCA), is known for its efficacy in treating Obsessive-compulsive Disorder (OCD). However, it is associated with several side effects, including urinary retention. This case report discusses the case of a 20-year-old male with OCD who developed urinary retention following clomipramine administration.
View Article and Find Full Text PDFExperience with the implementation of central venous catheters by medical oncologists in a non-surgical setting.
Sci Rep
January 2025
Medical Oncology Department, Central University Hospital of Asturias, Oviedo, Spain.
Totally implantable central venous catheters (CVCs) are widely used in the management of patients with malignant diseases. Conventionally, port implantations were carried out by general surgeons and vascular radiologists. In recent years, the medical staff of the Medical Oncology department at the Central University Hospital of Asturias (HUCA) has developed a simplified methodology for the routine implantation of these devices.
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