AI Article Synopsis
- The study examines aminolevulinic dehydratase (ALAD) activity in 293 individuals without occupational exposure to ALAD inhibitors, revealing no significant differences between genders despite variations in mean values.
- ALAD activity distribution was normal across both genders and varied significantly among different age groups, but no direct correlation was found between ALAD activity and blood hemoglobin concentration.
- Additionally, 32 participants exposed to lead were tested, with no correlation identified between blood lead levels and ALAD activity.
Article Abstract
The subject of the paper has been to check the aminolevulinic dehydratase (ALAD) activity in those with no occupational exposure to inhibitors of this enzyme. Altogether 293 persons have been examined, 132 women and 161 men, aged 20-69. The resultant ALAD activity distribution showed no differences between women and men, though statistically significant differences have been found between the mean values. The distribution did not deviate from normal in both groups. The analysis of ALAD activity distribution in particular age groups, whether female or male, showed statistically significant differences. No clear dependence between ALAD activity and haemoglobin concentration in blood has been found. On the other hand, clear differences in ALAD activity between groups of high and low haemoglobin concentrations have been found. In addition to the mentioned examinations, 32 persons (12 women and 20 men) presently exposed to lead had their lead concentration determined in blood. No correlations have been found between lead concentrations in blood and ALAD activity.
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