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Fatal Fulminant Epstein-Barr Virus (EBV) Encephalitis in Immunocompetent 5.5-Year-Old Girl-A Case Report with the Review of Diagnostic and Management Dilemmas.
Biomedicines
December 2024
Department of Pediatric Anesthesiology and Intensive Therapy, Medical University of Warsaw, 02-091 Warsaw, Poland.
Epstein-Barr virus (EBV) usually causes mild, self-limiting, or asymptomatic infection in children, typically infectious mononucleosis. The severe course is more common in immunocompromised patients. Neurological complications of primary infection, reactivation of the latent infection, or immune-mediated are well-documented.
View Article and Find Full Text PDFHyperventilation worsens inflammatory lung injury in spontaneously breathing rats.
J Bras Pneumol
December 2024
. Divisão de Pneumologia e Terapia Intensiva, Hospital Universitário, Universidade Federal de Juiz de Fora, Juiz de Fora (MG), Brasil.
Objectives: Here, we investigated the effects of hyperventilation on acute lung injury (ALI) in spontaneously breathing rats.
Methods: Wistar rats were randomized to receive either intraperitoneal lipopolysaccharides (LPS) or saline, and intravenous infusion of NH4Cl (to induce metabolic acidosis and hyperventilation) or saline. Four groups were established: control-control (C-C), control-hyperventilation (C-HV), LPS-control (LPS-C), and LPS-hyperventilation (LPS-HV).
Paradoxical metabolic acidosis after vomiting in children with spinal muscular atrophy: A report of 9 patients.
Arch Pediatr
October 2024
Pediatric Neurology & Intensive Care Unit, Assistance Publique des Hôpitaux de Paris, Hôpital Raymond-Poincaré, Garches, France; Simone Veil Health Science Center, Université Versailles SQY, Paris-Saclay, France.
Article Synopsis
- Spinal muscular atrophy (SMA) leads to severe metabolic acidosis in patients after mild vomiting, a serious and uncommon condition that can result in life-threatening complications.
- A study of 11 SMA patients revealed a median pH of 7.23 and low bicarbonate levels, with nearly half showing signs of ketoacidosis; hydration with glucose significantly improved their condition within 24-48 hours.
- The findings suggest that SMA patients are more vulnerable to ketoacidosis from fasting and have impaired buffering capacity, highlighting the need for prompt treatment to prevent exhaustion and potentially fatal outcomes.
Postoperative Symptomatic Cerebral Vasospasm: Requiring Attention Following an Uneventful Resection of an Epidermoid Cyst - A Case Report and Literature Review.
NMC Case Rep J
July 2024
Department of Neurosurgery, Hyogo Prefectural Kobe Children's Hospital, Kobe, Hyogo, Japan.
Cerebral vasospasm associated with epidermoid cyst can be caused by tumor content spillage, such as spontaneous rupture and postsurgical resection. Symptomatic cerebral vasospasm following the resection of an intracranial epidermoid cyst is a rare but serious complication that lacks a consensus on treatment. Case presentation: A 10-year-old girl underwent an uneventful complete resection of a left cerebellopontine angle epidermoid cyst.
View Article and Find Full Text PDFIntraoperative fat embolism syndrome associated with implantation of titanium sacroiliac joint fusion implants: a report of two cases.
J Spine Surg
March 2024
Department of Spine Surgery, University of Colorado, Aurora, CO, USA.
Background: For patients undergoing long-construct fusion surgeries, simultaneous sacroiliac joint (SIJ) fusion is a growing trend in spine surgery. Some options for posterior SIJ fusion include 3D-printed triangular titanium implants or self-harvesting SIJ screws. Both implants require fixation within the sacrum and ileum.
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