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Minute mesenchymal chondrosarcoma within osteochondroma: an unexpected diagnosis confirmed by HEY1-NCOA2 fusion.
Hum Pathol
November 2018
Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, Tokyo 104-0045, Japan; Rare Cancer Center, National Cancer Center Hospital, Tokyo 104-0045, Japan. Electronic address:
Article Synopsis
- A lesion on her rib was initially diagnosed as an osteochondroma and was surgically removed after being monitored for 3 years, revealing a small mesenchymal chondrosarcoma.
- The tumor showed specific genetic changes that were identified using advanced testing, and the patient has not experienced any recurrence 6 years post-surgery, underscoring the importance of thorough pathology exams and molecular testing for accurate diagnosis. *
Scoliosis in patients with multiple hereditary exostoses.
Eur Spine J
July 2015
Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan,
Purpose: To investigate the prevalence of and to identify independent predictors associated with scoliosis in patients with multiple hereditary exostoses (MHE).
Methods: Fifty patients with MHE were clinically examined, and the diagnosis of scoliosis was made based on radiographs. To classify disease severity, three classes based on the presence of deformities and functional limitations were defined.
Giant intra-articular extrasynovial osteochondroma of the knee: a report of two cases.
Open Orthop J
August 2012
Department of Orthopaedic Surgery, University of Rome Tor Vergata, Viale Oxford 81, 00133 Rome, Italy.
We report two cases of a giant extrasynovial osteochondroma of the knee located in the infrapatellar fat pad region, in two females who were 58 and 71 years old respectively. Both patients had noticed the mass many years before our first clinical observation. In both patients, at physical examination a solid, firm and hard mass was palpable in the anterior part of the knee in Hoffa's fat pad region, and the range of motion of the knee was severely restricted and painful.
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