The relationships between the states of vigilance and the interictal EEG, paroxysmal activities (PA) were studied in 20 adults with generalized primary epilepsy. Each patient was submitted to 1-5 nocturnal polygraphic recordings. Sleep and waking modify the PA densities: 8 patients had a waking PA increase, 7 a sleep PA increase and 5 exhibited no differences of PA density between sleep and waking. Within these groups there was also an influence of slow wave sleep stages on PA densities. The function of auto-correlation of PA did not exhibit any periodicity even after correction of the effects of the states of vigilance. In patients monitored several nights the evolution of the PA densities during the successive sleep cycles throughout the night did not usually reveal a clear and stable pattern.
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http://dx.doi.org/10.1016/s0370-4475(82)80045-2 | DOI Listing |
Neuropharmacology
January 2025
Nanhu Brain-computer Interface Institute, Hangzhou 311100, China; Department of Neurobiology and Department of Psychiatry of Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 310058 Hangzhou, China; Liangzhu Laboratory, MOE Frontier Science Center for Brain Science and Brain-machine Integration, State Key Laboratory of Brain-machine Intelligence, Zhejiang University, 1369 West Wenyi Road, Hangzhou 311121, China; NHC and CAMS Key Laboratory of Medical Neurobiology, Zhejiang University, Hangzhou 310058, China. Electronic address:
Anxiety, a future-oriented negative emotional state, is characterized by heightened arousal and vigilance. The elevated plus maze (EPM) test is a widely used assay of anxiety-related behaviors in rodents and shows a phenomenon where animals with prior test experience tend to avoid open arms in retest sessions. While this one-trial tolerance (OTT) phenomenon limits the reuse of the EPM test, the potential mechanisms remain unsolved.
View Article and Find Full Text PDFCognition
January 2025
School of Human Evolution and Social Change, Arizona State University, 900 South Cady Mall, Tempe, AZ 85287, USA; Institute of Human Origins, Arizona State University, 777 E University Drive, Tempe, AZ 85287, USA.
Cultural evolutionary theory has shown that social learning is adaptive across a broad range of conditions. While existing theory can account for why some social information is ignored, humans frequently under-utilise beneficial social information in experimental settings. One account of this is epistemic vigilance, whereby individuals avoid social information that is likely to be untrustworthy, though few experiments have directly tested this.
View Article and Find Full Text PDFChronobiol Int
January 2025
Laboratory of Braintime, Graduate Institute of Mind, Brain and Consciousness (GIMBC), Taipei Medical University, Taipei, Taiwan.
The intricate relationship between circadian rhythms and mood is well-established. Disturbances in circadian rhythms and sleep often precede the development of mood disorders, such as major depressive disorder (MDD), bipolar disorder (BD), and seasonal affective disorder (SAD). Two primary factors, intrinsic circadian clocks and light, drive the natural fluctuations in mood throughout the day, mirroring the patterns of sleepiness and wakefulness.
View Article and Find Full Text PDFCase Rep Gastrointest Med
January 2025
Department of Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, Michigan 48202, USA.
Colorectal cancer (CRC) continues to be a significant global health issue contributing to a high mortality rate. Despite advancements in treatment, the risk of recurrence remains due to inherent mutations and the rapid turnover of intestinal mucosa. We present an exceptionally rare case of CRC metastasis to the duodenum in a 42-year-old female who has been compliant with postsurgical surveillance.
View Article and Find Full Text PDFFront Microbiol
January 2025
Graduate Program in Virology, Evandro Chagas Institute - IEC/MS/SVSA, Ananindeua, Brazil.
Wild rodents serve as crucial reservoirs for zoonotic viruses. Anthropogenic and environmental disruptions, particularly those induced by mining activities, can destabilize rodent populations and facilitate the emergence of viral agents. In the Canaã dos Carajás and Curionópolis regions of Brazil, significant environmental changes have occurred due to mining expansion, potentially creating conditions conducive to the emergence of rodent-associated viral diseases.
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