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Efficacy of sorption-detoxication therapy (sorbent SUMS-1) in combined treatment of acute purulent paraproctitis was evaluated. Degree of endotoxication, state of postoperative wound, structural and morphological state of mucosous membrane of the rectum (light, electron microscopy, morphometry of biopsies) were studied. It was found that local use of sorbent increases efficacy of treatment of severe paraproctitis: endotoxicosis eliminates, regional hemo- and lympho-circulation improves, wound regeneration activates.

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Experimental estimation of properties of an activated carbonic fibrillar material "Dnipro" was conducted. Its application perspectivity while conduction of plasmo-, lympho- and hemosorption was proved.

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The results of immunogenetic screening of 300 patients with multiple sclerosis (MS) were subjected to factorial analysis. Nine significant factors indicative of secondary immunodeficiency were elucidated. The development and course of the disease were found to be affected by lipid metabolism disorders and endocrine deviations in the thymus-adrenal system.

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Results of the examination of 133 patients show sorption methods of detoxication to be effective means in the complex treatment of hepatic insufficiency. In hepatocerebral insufficiency however resulting from portal cirrhosis better results were obtained after lymphosorption. Hemosorption is indicated in cholemic intoxications as well as after liquidation of the obstruction of the common bile duct.

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