Bone density (bone mineral content/bone width) was determined by iodine-125 (125I)-photon absorptiometry in the distal third of the radius before and after successful parathyroidectomy in 37 patients with primary hyperparathyroidism. Bone density progressively declined during the two years immediately preceding surgery. It rose by 6.4% during the first year following surgery but remained stable thereafter. The results suggest that photon absorptiometry analysis of bone density may disclose continuing bone loss before surgery and may show a partial recovery of bone loss that may ensue after successful parathyroidectomy.
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http://dx.doi.org/10.1097/00004424-198211000-00013 | DOI Listing |
Gac Med Mex
January 2025
Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, United Kingdom.
FRAX, a risk calculator that provides individualized 10-year probabilities of hip and major osteoporotic fracture, has been widely used for fracture risk assessment since its launch in 2008. It is now incorporated into very many guidelines worldwide to inform osteoporosis management. In this review, we explore the development of FRAX and how it enhances fracture risk prediction as compared to use of bone mineral density alone, as well as approaches to utilizing FRAX in determining intervention and assessment thresholds.
View Article and Find Full Text PDFBiogerontology
January 2025
Department of Physiology, School of Medicine, University of Louisville, Louisville, KY, 40202, USA.
Alzheimer's disease (AD) and osteoporosis (OP) pose distinct but interconnected health challenges, both significantly impacting the aging population. AD, a neurodegenerative disorder characterized by memory impairment and cognitive decline, is primarily associated with the accumulation of abnormally folded amyloid beta (Aβ) peptides and neurofibrillary tangles in the brain. OP, a skeletal disorder marked by low bone mineral density, involves dysregulation of bone remodeling and is associated with an increased risk of fractures.
View Article and Find Full Text PDFBiometals
January 2025
School of Environment and Climate, Guangdong Key Laboratory of Environmental Pollution and Health, Jinan University, Guangzhou, 510632, China.
Bone mineral density (BMD) measured by T-score is strongly associated with bone health, but research on its association with metals in humans body remains limited. To investigate the relationship between metal exposure and BMD, numbers of 159 participants in eastern China were studied. Urine and blood samples were collected and levels of 20 metals in the samples were measured using Inductively Coupled Plasma-Mass Spectrometry (ICP-MS).
View Article and Find Full Text PDFClin Cosmet Investig Dent
January 2025
Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Purpose: Thyroid hormones have a catabolic effect on bone mineral homeostasis. Hypothyroid patients have shown changes in bone mineral density with increased risk for osteoporosis and bone fractures. Radiomorphometric parameters on panoramic images are good indicators of bone mineral density.
View Article and Find Full Text PDFNatl J Maxillofac Surg
November 2024
Department of Prosthodontics, BBD CODS, Lucknow, Uttar Pradesh, India.
Introduction: Dental implants are the most popular alternative to rehabilitation of missing teeth and oro-facial structures. The outcome of such procedures depends on various factors and most-importantly on the osseo-integation with the surrounding bone. The evaluation needs better visualization and evaluation using CBCT anaylsis and determination of HU, using an appropriate software.
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