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Ventriculoperitoneal shunt infection: insights from a single-center comparative analysis.
Neurosurg Rev
January 2025
Neurosurgery Division, Department of Surgery, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife, Nigeria.
Ventriculoperitoneal (VP) shunting is frequently associated with complications of which shunt-related infections are the most common. However, controversies still exist regarding the underlying factors. This study comparing peri-operative skin preparation agents was aimed at determining which factors among previously documented determinants of shunt infection are implicated in our practice setting.
View Article and Find Full Text PDFMinimally invasive endodontic treatment through the labial/buccal cervical approach - protocol and case series.
J Endod
January 2025
Department of Endodontics, Qingdao Stomatological Hospital Affiliated to Qingdao University, Qingdao, Shandong province, China. Electronic address:
Introduction: Traditional access cavity preparation involves removing the roof of the pulp chamber and smoothing the dentin bulges at the root canal orifice, thereby creating straight-line access. However, this may damage more healthy dental tissue and reduce the tooth's fracture resistance. This case series presents a novel minimally invasive endodontic protocol for one maxillary canine and four mandibular premolars, which required root canal therapy due to labial/buccal cervical decay that caused pulpitis or periapical periodontitis.
View Article and Find Full Text PDFEasy to use particle-mediated transport of various dissolved active agents into the hair follicles - A novel platform technology.
Int J Pharm
January 2025
Department of Pharmaceutics and Biopharmaceutics, Philipps University Marburg, Robert-Koch-Str. 4, 35037 Marburg, Germany.
The use of nanoparticulate systems for the transport of active ingredients into hair follicles has been researched for almost two decades, resulting in countless publications with a wide variety of particle types, release mechanisms and active ingredients. The production of a stable dispersion is often time-consuming and costly. In this publication, we demonstrate for the first time that simply adding diverse submicron particles to a drug solution significantly increases follicular penetration depth by over 160% to 190%, allowing the targeting of subinfundibular structures.
View Article and Find Full Text PDFEfficacy of 0.2% povidone-iodine and 0.1% polyhexamethylene biguanide as preoperative antiseptics in equine ophthalmic procedures.
Vet Ophthalmol
December 2024
Unit for Ophthalmology, Veterinary Hospital Freie Universität Berlin, Berlin, Germany.
Objective: This retrospective study evaluates the efficacy of povidone-iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures.
Animals Studied: Horses that underwent routine ophthalmic surgery and procedures.
Procedures: Data were collected retrospectively from the medical records of equine patients undergoing ophthalmic procedures.
A New Approach to Evaluate the Bactericidal Activity of Different Antiseptic Ophthalmic Preparations Used as Surgical Prophylaxis.
Antibiotics (Basel)
November 2024
Department of Infectious-Tropical Diseases and Microbiology, IRCCS Sacro Cuore-Don Calabria Hospital, 37024 Negrar di Valpolicella, Italy.
: A survey conducted by the European Observatory on Cataract Surgery showed high heterogeneity in the use of antiseptics both preoperatively and in the operating room, highlighting the absence of a global consensus regarding ocular infection prophylaxis in cataract surgery. : The antibacterial activity of seven antiseptic ophthalmic formulations (AOFs) registered as medical devices and the two most common disinfectants were evaluated in vitro against five bacterial species. The viability of bacterial strains after exposure to the antiseptic was evaluated with different techniques: the in vitro Minimum Inhibitory Concentration and the subsequent Minimum Bactericidal Concentration, performed on liquid and solid culture medium.
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