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Utilizing Preoperative Rectus Sheath Blocks to Decrease Opioid Administration During Pediatric Umbilical Hernia Repair.
J Pediatr Surg
January 2025
Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA; Division of Pediatric Surgery, Arkansas Children's Hospital, Little Rock, AR, USA.
Introduction: Regional anesthetic blocks are an adjunct to decrease pediatric opioid utilization and improve perioperative pain control. We compared opioid use in patients who underwent umbilical hernia repair (UHR) with or without preoperative bilateral rectus sheath block (BRSB).
Methods: We conducted a single-center retrospective cohort study evaluating opioid use in patients <18 years who underwent an UHR.
Bright and Specific Targeting of Metastatic Lymph Nodes in Orthotopic Mouse Models of Gastric Cancer with a Fluorescent Anti-CEA Antibody.
Ann Surg Oncol
January 2025
Department of Surgery, University of California San Diego, La Jolla, CA, USA.
Background: Gastric cancer poses a major diagnostic and therapeutic challenge. Improved visualization of tumor margins and lymph node metastases with tumor-specific fluorescent markers could improve outcomes.
Methods: To establish orthotopic models of gastric cancer, one million cells of the human gastric cancer cell line, MKN45, were suspended in 50 μl of equal parts PBS and Matrigel and injected into the nude mouse stomach with a 29-gauge needle.
Cannabinoids for Acute Postoperative Pain Management: A Systematic Review and Meta-Analysis of Clinical Trials.
Eur J Pain
March 2025
Universidad del Bosque, Bogotá, Colombia.
Background: Poor acute postoperative pain control, coupled with the use of intravenous medications with a limited and unsafety efficacy spectrum, has led to new therapeutic alternative explorations to reduce adverse events while increasing its analgesic efficacy. There cannabinoids have been proposed as a useful control agent in post-surgical pain. Nevertheless, to date, there is no solid evidence to evaluate them.
View Article and Find Full Text PDFOtitis Media and Its Intracranial Complications: A Delicate Scenario.
Cureus
December 2024
Internal Medicine, Pedro Hispano Hospital, Matosinhos Local Health Unit, Matosinhos, PRT.
Intracranial complications of otitis media are rare but pose a significant risk of morbidity and mortality. We report a case of a 27-year-old man with cognitive impairment who presented with fever, right-sided otalgia, otorrhea, and vomiting for three days. His neurological examination was unremarkable, and a brain computed tomography (CT) revealed right-sided otomastoiditis without intraparenchymal lesions.
View Article and Find Full Text PDFA Comprehensive Comparative Study of Direct Vision Internal Urethrotomy and Urethroplasty in Short-Segment Bulbar Urethral Strictures.
Cureus
December 2024
Department of Urology, Indira Gandhi Institute of Medical Sciences, Patna, IND.
Background Currently, there is no data on the prevalence of urethral stricture illness in India. For short-segment bulbar urethral stricture, end-to-end anastomosis is the gold standard of care. The purpose of this study was to find where the direct vision internal urethrotomy (DVIU) exists in today's era.
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