Glutaraldehyde has been used for electron microscopic studies of mitochondrial volume fluctuation during Sr2+--induced oscillation of ion fluxes. It has been shown that the observed ultrastructural and fluctuations of mitochondria is reversible to correlate with light-scattering value as well as to the direction of ion transfer. Determination of the intramitochondrial volume at different stages of oscillatory cycle shows the increase in the volume during the process of swelling up to 2.4-5.6 times compared with the shrihkate state.
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