Cholelithiasis and cholecystitis are uncommon in childhood and adolescence. Misconceptions as to the aetiology, natural history, diagnosis, and therapy of these conditions prompted us to review our experience. Nineteen patients ranging in age from 7 to 18 years underwent cholecystectomy for gallstones at the University of Illinois Hospital, Chicago, between June 1970 and June 1979. Seventeen patients were female and 2 male (ratio 8.5:1). The cause was unknown in 12 patients (63%) but in 7 patients (37%) haematological disease was the underlying disorder. The most common presenting symptom (95%) was vague right upper quadrant or epigastric pain, often ignored or mistaken for peptic ulcer pain. Oral cholecystography demonstrated gallstones in 15 of 16 patients. Ultrasonography, used more recently, was positive in 3 patients intra-operative cholangiography in 12 patients, and common duct exploration in 1 additional patient, failed to demonstrate calculi. No patients were readmitted for recurrent or retained biliary calculi after cholecystectomy.
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Orphanet J Rare Dis
January 2025
Department of Pediatric Gastroenterology and Nutrition, Amsterdam UMC, Emma Children's Hospital, Vrije Universiteit, Amsterdam, The Netherlands.
Background: Achalasia is a rare esophageal motility disorder with an estimated annual incidence of 1-5/100.000 and a mean age at diagnosis > 50 years of age. Only a fraction of the patients has an onset during childhood (estimated incidence of 0.
View Article and Find Full Text PDFBMJ Open
January 2025
Clinical and Translational Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
Introduction: The global prevalence of people living with overweight has tripled since 1975 and more than 40% of Danish women enter pregnancy being overweight. With the increasing rates of obesity observed in children, adolescents and adults, there is an urgent need for preventive measures. Risk factors for childhood obesity include maternal overweight or obesity before conception and excessive weight gain during pregnancy.
View Article and Find Full Text PDFRadiol Clin North Am
March 2025
Department of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
Pediatric patients are affected by a wide variety of pulmonary vascular diseases ranging from congenital anomalies diagnosed at birth to acquired diseases that present later in childhood and into adolescence. While some pulmonary vascular diseases present similarly to those seen in adults, other forms are unique to children. Knowledge of the characteristic imaging features of these diseases is essential to facilitate prompt diagnosis and guide clinical management.
View Article and Find Full Text PDFChild Abuse Negl
January 2025
Center for Clinical Big Data and Statistics of the Second Affiliated Hospital Zhejiang University School of Medicine, School of Public Health Zhejiang University School of Medicine, Hangzhou China. Electronic address:
Background: Nurses demonstrate a greater vulnerability to developing depressive and anxiety symptoms compared to the general population. Adverse Childhood Experiences (ACEs) are known risk factors for mental health issues, but impact of timing of these experiences remains unclear.
Objective: To investigate associations between timing of ACEs and depressive, anxiety, comorbid symptoms.
Pflugers Arch
January 2025
Leibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
The global increase of overweight and obesity in children and adults is one of the most prominent public health threats, often accompanied by insulin resistance, hypertension, and dyslipidemia. The simultaneous occurrence of these health problems is referred to as metabolic syndrome. Various criteria have been proposed to define this syndrome, but no general consensus on the specific markers and the respective cut-offs has been achieved yet.
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