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A Rare Case of Lemierre's Syndrome Caused by Streptococcus pyogenes.
Cureus
December 2024
Internal Medicine Department, Unidade Local de Saúde Entre Douro e Vouga, Santa Maria da Feira, PRT.
Lemierre's syndrome (LS) is a rare condition characterized by septic thrombophlebitis of the internal jugular vein (IJV). Typically, the primary infection originates in the oropharynx, progressing to the lateral pharyngeal space, IJV, and potentially leading to bacteremia. Through septic embolization, these patients can develop severe complications, underscoring the importance of early diagnosis.
View Article and Find Full Text PDFCausal Association Between Childhood Body Mass Index and Phlebitis and Thrombophlebitis: An Analysis Using Mendelian Randomization.
Lymphat Res Biol
January 2025
Department of Neonatology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, China.
Research has indicated a link between obesity and a greater likelihood of venous disorders. However, the specific relationship between obesity in children and conditions such as phlebitis and thrombophlebitis remains undetermined. To explore this, we undertook a two-sample Mendelian randomization (MR) study to investigate the possible causal impact of childhood body mass index (BMI) on the development of phlebitis and thrombophlebitis.
View Article and Find Full Text PDFCardiovascular Events Associated with CDK4/6 Inhibitors: A Safety Meta-Analysis of Randomized Controlled Trials and a Pharmacovigilance Study of the FAERS Database.
Am J Cardiovasc Drugs
December 2024
Breast Disease Diagnosis and Treatment Center of Affiliated Hospital of Qinghai University and Affiliated Cancer Hospital of Qinghai University, Xining, 810000, China.
Background: CDK4/6 inhibitors are highly valued, but the incidence of cardiovascular adverse events (CVAEs) associated with CDK4/6 inhibitors is not clear.
Objective: Our aim was therefore to assess the risk of developing CVAEs associated with CDK4/6 inhibitors, by conducting a systematic review and meta-analysis of randomized controlled trials (RCTs), along with a pharmacovigilance study of the FDA Adverse Event Reporting System (FAERS) database.
Methods: Eligible CVAEs were extracted from the ClinicalTrials.
Abnormal microRNA expression profile at early stages of gestation in pregnancies destined to develop placenta previa.
Front Med (Lausanne)
December 2024
Institute for the Care of the Mother and Child, Third Faculty of Medicine, Charles University, Prague, Czechia.
Article Synopsis
- Placenta previa is a condition where the placenta implants abnormally in the lower uterus, leading to serious risks for both the mother and fetus, including hemorrhage and stillbirth.
- This study focused on analyzing microRNA expression in the blood during the first trimester of pregnancies that later developed placenta previa, comparing them to normal pregnancies.
- The results showed that several microRNAs were downregulated in those pregnancies, with a combination of seven specific microRNAs accurately distinguishing between healthy and placenta previa pregnancies early on.
Leukopenia-a rare complication secondary to invasive liver abscess syndrome in a patient with diabetes mellitus: A case report.
World J Gastrointest Surg
October 2024
Department of Gastroenterology, Nanjing Lishui People's Hospital, Zhongda Hospital Lishui Branch, Southeast University, Nanjing 211200, Jiangsu Province, China.
Background: Thrombocytopenia is a common complication of invasive liver abscess syndrome (ILAS) by () infection, which indicates severe infection and a poor prognosis. However, the presence of leukopenia is rare. There are rare reports on leukopenia and its clinical significance for ILAS, and there is currently no recognized treatment plan.
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