Investigation of the membrane potential of Neurospora crassa mycelial cells was carried out by standard microelectrode technique. The resting potential is equal to--156 +/- 11 mV (negative inside the cell). The light of the spectrum blue-violet zone causes transient hyperpolarization of the cell membrane reaching --38 +/- 5 mV after 25 minutes of illumination.

Download full-text PDF

Source

Publication Analysis

Top Keywords

[refractory properties
4
properties cardiac
4
cardiac tissue
4
tissue fast
4
fast sodium
4
sodium current
4
current decrease
4
decrease comparison
4
comparison atrium
4
atrium ventricle]
4

Similar Publications

"Innovative multidisciplinary care in pediatric magnet aspiration: A case report".

Int J Surg Case Rep

January 2025

Department of Pediatric Surgery, The University of Child Health Sciences and The Children's Hospital, Lahore, Lahore - Kasur Rd, Nishtar Town, Lahore, Punjab, Pakistan 54000.

Introduction: Foreign body (FB) inhalation is a potentially life-threatening condition in children. Magnets, being rare, aspirated objects, pose significant threat due to their physical and magnetic properties.

Case Presentation: A 10-year-old girl with a history of magnet aspiration went into respiratory distress due to dislodgement of magnet to opposite main bronchus following failed attempt of removal via Rigid Bronchoscopy.

View Article and Find Full Text PDF

Radiopharmaceuticals and their applications in medicine.

Signal Transduct Target Ther

January 2025

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 100050, Beijing, China.

Article Synopsis
  • Radiopharmaceuticals deliver radionuclides to specific lesions, providing targeted diagnosis and treatment for diseases, particularly those resistant to standard therapies.
  • The FDA's approval of agents like [Lu]Lu-DOTA-TATE and [Ga]Ga-PSMA-11 marks significant progress in clinical oncology, enhancing the use of radiotheranostics in personalized medicine.
  • Advancements in radiopharmaceutical development focus on targeting a wider array of diseases, improving therapeutic efficacy, and expanding applications to neurodegenerative and cardiovascular conditions.
View Article and Find Full Text PDF

Fluorination of Aza-BODIPY for Cancer Cell Plasma Membrane-Targeted Imaging and Therapy.

ACS Appl Mater Interfaces

January 2025

State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences-Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430071, China.

Photodynamic therapy (PDT) holds great potential in cancer treatment, leveraging photosensitizers (PSs) to deliver targeted therapy. Fluorination can optimize the physicochemical and biological properties of PSs for better PDT performance. Here, we report some high-performance multifunctional PSs specifically designed for cancer PDT by fluorinating aza-BODIPY with perfluoro--butoxymethyl (PFBM) groups.

View Article and Find Full Text PDF

Introduction: Metabolic acidosis, marked by decreased plasma bicarbonate and arterial pH, is a common complication following extensive abdominal surgeries. D-lactate acidosis presents additional diagnostic challenges due to nonspecific symptoms.

Presentation Of Case: A 65-year-old woman with hypertension and morbid obesity was admitted to the ICU for intestinal obstruction and peritonitis due to an incarcerated hernia.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!