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Impact of xylene exposure during organogenesis on foeto-placental efficiency and foetal viability: Exploring its association with oxidative stress-induced inflammation and apoptosis .
Toxicol Ind Health
December 2024
Department of Anatomy, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
The potential maternal and foetal toxicity resulting from exposure to xylene at or below the allowable limit of 100 ppm during gestation is not thoroughly studied. The aim of this study was to investigate maternal and foetal outcomes following prenatal exposure to xylene during organogenesis. Pregnant Sprague Dawley (SD) rats were administered intraperitoneal (IP) corn oil (vehicle), 100, 500, and 1000 parts per million (ppm) of xylene from gestational day (GD) 6 until GD17.
View Article and Find Full Text PDFThe effects of prenatal methylmercury exposure on trace element and antioxidant levels in rats following 6-hydroxydopamine-induced neuronal insult.
Metab Brain Dis
June 2014
Discipline of Human Physiology, School of Laboratory Medicine and Medical Sciences, College of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4000, South Africa,
Methylmercury (MeHg) is a metal toxin found commonly in the environment. Studies have shown severe neurotoxic effects of MeHg poisoning especially during pregnancy where it crosses the foetoplacental and the blood brain barrier of the foetus leading to neurodevelopmental deficits in the offspring. These deficits may predispose offspring to neurodegenerative diseases later in life.
View Article and Find Full Text PDF[Fetal supraventricular tachycardia associated with anasarca: poor prognosis despite treatment. Apropos of two cases].
Arch Mal Coeur Vaiss
May 1998
Clinique Saint-Joseph, Colmar.
Two cases of foetal supraventricular tachycardia with hydrops with fatal outcomes illustrate the poor general prognosis of this condition. The absence of therapeutic consensus, of large series in the existing literature, does not prevent logical and reasonable management based on rhythmological, pharmacological and prognostic criteria. A combined approach associating antiarrhythmic therapy by the transplacental and intrafunicular approaches seems acceptable now that funicular puncture can be undertaken easily, and certain antiarrhythmic molecules suggest encouraging results.
View Article and Find Full Text PDFA murine model for the study of the impact of Aspergillus fumigatus inoculation on the foeto-placental unit.
Mycopathologia
October 1990
National Veterinary Laboratory, Copenhagen V, Denmark.
Pregnant female BALB/c mice were inoculated intravenously with Aspergillus fumigatus conidia in different concentrations (1 x 10(1)-1 x 10(8)) on day 10 of pregnancy. Pregnancy was confirmed by the presence of murine alpha-fetoprotein (m-AFP) in the maternal circulation. Conidia inoculation of 1 x 10(3) and greater significantly (p less than 0.
View Article and Find Full Text PDF[Foetoplacental lesions caused by human listeriosis. Seven cases].
Arch Anat Cytol Pathol
December 1982
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