A histologic investigation of the liver was carried out with lambs after experimental and spontaneous infection with Cysticercul tenuicolis. Varying in character was the response of the host to the parasite at the site of localization. In some cases the connective tissue component was prevailing, while in others there was predominantly a cell-inflammatory demarcation around the cysts. There were also cases presenting no local reaction around the larvae. The development of progressive degenerative and necrotic lesions within the liver parenchyma was encountered which, by the end of the experimental period invariably resulted in cirrhosis.
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