Fifty six patients undergoing elective abdominal surgery were investigated preoperatively with tests of coagulation, platelet function and fibrinolysis. Ten patients developed postoperative deep vein thrombosis, detected by the labelled fibrinogen uptake test and confirmed by ascending phlebography. None of the tests showed a statistically significant difference between the group mean of patients who developed DVT and of those who did not. Potential discriminators were used to derive a prognostic index for prediction of patients who would develop postoperative DVT. An index based on two preoperative blood tests i.e. three hour fibrin digestion and APTT had a successful prediction rate of 59 percent.

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http://dx.doi.org/10.1016/0049-3848(82)90193-1DOI Listing

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