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To evaluate the effectiveness of syntonic phototherapy and compare it with partial time occlusion to improve visual acuity in cases of refractive amblyopia. This study is a prospective, comparative, and randomized study. It included 40 patients.

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: Chronic pelvic pain (CPP) is a common complication of pelvic inflammatory disease (PID). Although acupuncture has been increasingly used for the management of CPP, there is insufficient research to support the use of laser stimulation of sensitized acupoints. This study aimed to investigate the effects of laser on sensitized acupoints on pelvic pain perception and quality of life in women with pelvic inflammatory disease.

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Background: Despite the routine clinical use of extracorporeal photopheresis (ECP) for the last decades, there has been no sufficient investigation on the intra-apheresis dynamics of mononuclear cells (MNCs).

Objective: This research aims to verify the "intra-apheresis recruitment" (IAR) of MNCs, which may be particularly useful in cases with low preapheresis MNC counts.

Methods: Prospective data of ECP procedures for patients with multiple sclerosis (MS) in the context of the PHOMS study (NCT05168384) were analyzed.

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Chronobiologic treatments for mood disorders.

Handb Clin Neurol

January 2025

Division of Neuroscience, IRCCS Ospedale San Raffaele, Milano, Italy.

Chronotherapeutics are nonpharmacologic interventions whose development stems from investigations into sleep and circadian rhythm abnormalities associated with mood disorder. These therapies utilize controlled exposure to environmental cues (light, darkness) to regulate biologic rhythms. They encompass sleep-wake manipulations (partial/total sleep deprivation, sleep phase adjustment) and light therapy approaches.

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Vitiligo is a chronic autoimmune pigmentation disorder shaped by a complex interplay of genetic predispositions and environmental triggers. While conventional therapies-phototherapy, corticosteroids, and immunosuppressants-can be effective, their benefits are often partial and temporary, with recurrence common once treatment stops. As such, there is increasing interest in exploring complementary approaches that may offer a more sustainable impact.

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