Loin-pain-haematuria syndrome.

J Indian Med Assoc

Published: May 1982

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The purpose of this retrospective review is to question the validity of the condition 'loin pain haematuria syndrome' (LPHS). We highlight the possibility that most patients regarded as having LPHS have a psychiatric/psychological basis for their symptoms, particularly loin pain. Because of this, and because it recurs despite treatment, the review also questions the use of treatments that are invasive, expensive, and carry considerable morbidity.

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Article Synopsis
  • * The majority of patients were women (97%) with a mean age of 32 years; 63% experienced significant pain improvement post-surgery, and complications mainly involved mild cases (47% type 1 and 9% type 3) with 28% developing acute kidney injury.
  • * The findings suggest that RAKAT is a viable surgical option for these conditions, demonstrating a complication rate comparable to other surgical methods without any recorded deaths or
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A 32-year-old male patient presented the clinical picture of loin pain haematuria syndrome with pain attacks accompanied by macrohaematuria. In renal biopsy, the preglomerular vessels showed segmental wall hyalinosis in the sense of low-grade nephrosclerosis, and glomerular capillaries with slightly but diffusely thickened, non-split basal membranes on electron microscopy. Notable were irregularly deformed, different dense erythrocytes in the glomerular capillaries, and several tubular lumina.

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Dorsal Root Ganglion Stimulation: A Treatment Option for Chronic Pain Due to Refractory Loin Pain Haematuria Syndrome.

Neuromodulation

December 2017

Department of Anaesthesiology and Pain Management, Diakonessenhuis Utrecht/Zeist, PO Box 80250, 3508 TG Utrecht, the Netherlands.

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Background: Loin pain haematuria syndrome (LPHS) and autosomal dominant polycystic kidney disease (ADPKD) are the most important non-urological conditions to cause chronic severe kidney-related pain. Multidisciplinary programmes and surgical methods have shown inconsistent results with respect to pain reduction. Percutaneous catheter-based renal denervation (RDN) could be a less invasive treatment option for these patients.

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