After administration to rats in a dose of 200-400 mg/kg on days 14 and 15 of the pregnancy the hypnotic drug glutethimide induces in the rat progeny variations in the orienting-motor activity, latent period of runnings and raises the frequency of urinations upon training in a maze. The effect of glutethimide on the orienting-motor behavior was seen only in the first generation of the animals and was absent from the second generation animals.
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