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Oral supplementation with propionate is reflected in the serum of healthy individuals.
Ther Adv Neurol Disord
January 2025
Department of Neurology, Ruhr-University Bochum, St. Josef-Hospital, Gudrunstr. 56, Bochum 44791, Germany.
Background: Short-chain fatty acids (SCFAs), including propionic acid (PA), are key in immunological research. Supplementing PA has shown benefits for autoimmune diseases. A comprehensive understanding of the PA pharmacokinetics is essential for the optimal design and execution of studies utilizing orally administered PA.
View Article and Find Full Text PDFEffect of different cold acclimation methods on the exercise capacity of mice in low-temperature environments.
J Therm Biol
January 2025
China Institute of Sport Science, Beijing, 100061, China. Electronic address:
Objective: This study aimed to evaluate the effects of different cold acclimation strategies on exercise performance in male mice exposed to low-temperature environments.
Methods: Male mice were subjected to five distinct acclimation regimens over 8 weeks: immersion at 10 °C (10 °CI) or 20 °C (20 °CI), swimming at 10 °C (10 °CS), 20 °C (20 °CS), or 34 °C (34 °CS). During the first 2 weeks, the acclimation time progressively decreased from 30 min to 3 min per day, and the water temperatures were lowered from 34 °C to the target levels, followed by 6 weeks of consistent exposure.
Evaluation of Faecal Microbiota Following Probiotics in Infants of Mothers with Gestational Diabetes Mellitus Trial: Protocol for Double-Blind Placebo-Controlled Randomized Trial.
Microorganisms
January 2025
Department of Neonatology, King Edward Memorial Hospital, Perth, WA 6008, Australia.
(1) Background: The incidence of gestational diabetes mellitus (GDM) is rising globally. The current evidence indicates that GDM, especially in conjunction with maternal overweight, can alter the composition of infants' gut microbiota, potentially increasing the risk of inflammatory diseases, metabolic disorders, and neurodevelopmental issues later in life. Probiotic supplantation early in life might establish eubiosis and mitigate future complications.
View Article and Find Full Text PDFXylooligosaccharides: A comprehensive review of production, purification, characterization, and quantification.
Food Res Int
February 2025
Nottingham Ningbo China Beacons of Excellence Research and Innovation Institute, University of Nottingham Ningbo, Ningbo 315100, China. Electronic address:
Xylooligosaccharides (XOS), short-chain polymers with prebiotic properties, have gained significant commercial attention over the past few decades due to their potential as nutraceutical components. Derived from lignocellulosic biomass (LCB), XOS serve as health promoting compounds with applications across multiple sectors, including food pharmaceutical and cosmetic. This comprehensive review provides an overview of XOS production, purification, characterization, and quantification, highlighting their derivation from various sources such as agricultural waste, agro-economical forest residues, and nutrient-dense energy crops.
View Article and Find Full Text PDFComprehensive quantification of C4 to C26 free fatty acids using a supercritical fluid chromatography-mass spectrometry method in pharmaceutical-grade egg yolk powders intended for total parenteral nutrition use.
Anal Bioanal Chem
January 2025
Department of Chemistry - Biomedical Center, Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden.
Free fatty acids (FFAs) are important energy sources and significant for energy transport in the body. They also play a crucial role in cellular oxidative stress responses, following cell membrane depolarization, making accurate quantification of FFAs essential. This study presents a novel supercritical fluid chromatography-mass spectrometry (SFC-MS) method using selected ion recording in negative electrospray ionization mode, enabling rapid quantification of 31 FFAs within 6 min without derivatization.
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