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Screening of cytokines-cytokine receptor-associated genes in childhood asthma based on bioinformatics.
Integr Biol (Camb)
January 2025
Changchun University of Chinese Medicine, No. 1035, Boshuo Road, Jingyue High tech Industrial Development District, Changchun City Jilin Province 130117, China.
Purpose: To develop efficient diagnostic and treatment approaches, gaining an in-depth knowledge of the molecular mechanisms and potential targets causing childhood asthma is of utmost significance.
Methods: Childhood asthma datasets were obtained from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) between asthmatic child and healthy people were screened by the Limma package.
Treatment of acute urticaria: A systematic review.
J Eur Acad Dermatol Venereol
November 2024
SKIN Research Group, Vrije Univeristeit Brussel (VUB), Brussels, Belgium.
There are only a few clinical trials which address the treatment of acute urticaria (AU). Especially, the added value of systemic corticosteroids to antihistamines is unclear in treatment of severe AU. To review the existing evidence-based approaches for AU treatment.
View Article and Find Full Text PDFCimetidine and racecadotril: Unusual culprit drugs of a severe cutaneous adverse reaction.
Contact Dermatitis
November 2022
Service de Dermatologie, AP-HP, Hôpital Henri Mondor, Créteil, France.
Clinical effect of alfacalcidol in children with Henoch-Schönlein purpura: a prospective randomized controlled trial.
Zhongguo Dang Dai Er Ke Za Zhi
August 2021
Department of Pediatrics, First People's Hospital of Yibin, Yibin, Sichuan 644000, China.
Objectives: To study the effects of alfacalcidol on serum 25-(OH)D level, cellular immune function, and inflammatory factors in children with Henoch-Schönlein purpura (HSP).
Methods: A total of 200 children with HSP were prospectively enrolled from June 2018 to June 2020. According to the random number table method, they were divided into an observation group and a control group (=100 each).
Hydroxychloroquine efficacy and safety in preventing SARS-CoV-2 infection and COVID-19 disease severity during pregnancy (COVID-Preg): a structured summary of a study protocol for a randomised placebo controlled trial.
Trials
July 2020
ISGlobal, Hospital Clínic-Universitat de Barcelona, Barcelona, Spain.
Objectives: The primary objectives of the study are: 1. To assess the effect of hydroxychloroquine (HCQ) in reducing SARS-CoV-2 viral shedding by PCR in infected pregnant women with mild symptoms. 2.
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