The sequence of DNA replication was studied within the inactive X chromosome in human lymphocytes, by means of the FPG method. Several variants of the replication sequence were found. The number of variants in the cells of a single donor exceeded 2 in each of the 4 normal individuals studied. The phenomenon is discussed with respect to the regulation of DNA synthesis and to the cell differentiation process.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/BF00330363 | DOI Listing |
Publication Analysis
Top Keywords
inactive chromosome
8
replication variants
4
variants human
4
human inactive
4
chromosome variability
4
variability lymphocytes
4
lymphocytes single
4
single individuals
4
individuals sequence
4
sequence dna
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!