Surveys of antiglobulin test procedures and reagents were undertaken in 1979-1980 as part of a national external quality assessment scheme in compatibility testing. An extraordinary lack of standardization was revealed. In addition, practices underwent considerable changes over this period. The use of tube and of low ionic strength solution (LISS) techniques increased whilst the use of tile and of albumin-antiglobulin techniques declined. Performance in compatibility test exercises was significantly better with tube techniques than with tile techniques in 9/22 incompatibilities. Performance with LISS techniques was occasionally significantly better than with normal ionic strength techniques. Performance with albumin-antiglobulin techniques was occasionally significantly worse than in the absence of albumin. To varying extents significant relationships were found between performance and cell concentration, serum/cell concentration ratio, antiglobulin reagent and method of reading the results.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Development of the Lee Symptom Scale-Skin Sclerosis for chronic GVHD-associated sclerosis.
Blood
January 2025
Fred Hutchinson Cancer Center, Seattle, Washington, United States.
Sclerosis is a highly morbid manifestation of chronic GVHD (cGVHD), associated with distressing symptoms and significant long-term disability. A patient-reported outcome measure (PRO) for cGVHD-associated sclerosis is essential to advance therapeutic trials. We aimed to develop a PRO for adults with cGVHD-associated sclerosis and evaluate and refine its content validity.
View Article and Find Full Text PDFCD9/SOX2-positive cells in the intermediate lobe of the rat pituitary gland exhibit mesenchymal stem cell characteristics.
Cell Tissue Res
January 2025
Laboratory of Anatomy and Cell Biology, Department of Health Sciences, Kyorin University, 5-4-1 Shimorenjaku, Mitaka, Tokyo, 181-8612, Japan.
Adult tissue stem cells of the anterior pituitary gland, CD9/SOX2-positive cells, are believed to exist in the marginal cell layer (MCL) bordering the residual lumen of the Rathke's pouch. These cells migrate from the intermediate lobe side of the MCL (IL-MCL) to the anterior lobe side of the MCL and may be involved in supplying hormone-producing cells. Previous studies reported that some SOX2-positive cells of the anterior lobe differentiate into skeletal muscle cells.
View Article and Find Full Text PDFElectron-Rich Heptacyclic S,N Heteroacene Enabling C-Shaped A-D-A-type Electron Acceptors With Photoelectric Response beyond 1000 Nm for Highly Sensitive Near-Infrared Photodetectors.
Adv Sci (Weinh)
January 2025
Department of Applied Chemistry, National Yang Ming Chiao Tung University, Hsinchu, 30010, Taiwan.
A highly electron-rich S,N heteroacene building block is developed and condensed with FIC and Cl-IC acceptors to furnish CT-F and CT-Cl, which exhibit near-infrared (NIR) absorption beyond 1000 nm. The C-shaped CT-F and CT-Cl self-assemble into a highly ordered 3D intermolecular packing network via multiple π-π interactions in the single crystal structures. The CT-F-based organic photovoltaic (OPV) achieved an impressive efficiency of 14.
View Article and Find Full Text PDFElectrically Active Biomaterials for Stimulation and Regeneration in Tissue Engineering.
J Biomed Mater Res A
January 2025
Department of Biomedical Engineering, University of Connecticut, Storrs, Connecticut, USA.
In the human body, bioelectric cues are crucial for tissue stimulation and regeneration. Electrical stimulation (ES) significantly enhances the regeneration of nerves, bones, cardiovascular tissues, and wounds. However, the use of conventional devices with stimulating metal electrodes is invasive and requires external batteries.
View Article and Find Full Text PDFMapping an evidence-based end-of-life care framework for older adults in Chinese nursing homes: protocol for a scoping review.
BMJ Open
December 2024
School of Psychology, Wenzhou-Kean University, China, Wenzhou, Zhejiang, China.
Introduction: End-of-life care is essential for older adults aged ≥60, particularly those residing in long-term care facilities, such as nursing homes, which are known for their home-like environments compared with hospitals. Due to potential limitations in medical resources, collaboration with external healthcare providers is crucial to ensure comprehensive services within these settings. Previous studies have primarily focused on team-based models for end-of-life care in hospitals and home-based settings.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!