[Morphofunctional state of the gastric mucosa in primary, combined and secondary stomach ulcer].

The morphofunctional condition of the gastric mucosa was studied in primary, combined, and secondary peptic ulcers. The secretory function of the stomach in primary ulcers was found not to differ from that in normal subjects. An increase in the number of all kinds of epithelial cells of fossi and glands of the fundal part was observed, the percentage ratio of the cells not changing significantly. In secondary peptic ulcers arising in the presence of long-existing stenosing duodenal ulcers, that is due to gastrostasis, the secretory function was markedly increased. In this condition there was a significant increase in the number of principal and parietal cells. Their ultrastructure indicated a high functional activity. No principal differences in the condition of the secretory function of the stomach in patients with combined and secondary ulcers were found.