Inhibitory effects of certain tripeptide aldehydes on both thrombin and trypsin have been found to be strongly substrate-dependent. These compounds should therefore be considered as inhibitors of the particular proteolytic reaction for which they had been designed rather than real enzyme inhibitors, i.e. protein or polypeptide proteinase inhibitors of natural origin.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1399-3011.1978.tb02889.x | DOI Listing |
Publication Analysis
Top Keywords
thrombin trypsin
8
tripeptide aldehydes
8
inhibition thrombin
4
trypsin tripeptide
4
aldehydes inhibitory
4
inhibitory effects
4
effects tripeptide
4
aldehydes thrombin
4
trypsin substrate-dependent
4
substrate-dependent compounds
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!