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China officinalis as Possible Homeopathic Prophylaxis for the Brazilian Dengue Epidemic.
Homeopathy
December 2024
Hahnemannian George Galvão Institute (IHGG), São Paulo, Brazil.
Dengue, a hyperendemic arbovirus thriving in tropical and sub-tropical climates globally, has seen a significant surge in Brazil over the past 5 years. Presently, the country faces an epidemic, posing a huge challenge to Public Health authorities due to the potentially lethal nature of severe infections. Based on Hahnemannian concepts and on the historically reported efficacy of homeopathy in fighting epidemics, this study aimed to provide supporting evidence for a homeopathic genus epidemicus approach to prevent severe forms of dengue.
View Article and Find Full Text PDFA Systematic Review on the Antimicrobial Activity of Andrographolide.
J Microbiol Biotechnol
November 2024
Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan 16150, Malaysia.
Andrographolide, a bioactive compound from Andrographis paniculata, has gained attention for its antimicrobial properties, which include antibacterial, antiviral, antifungal, and antiprotozoal effects. As an herbal extract used in traditional medicines, andrographolide also shows promise for developing new antimicrobial agents, especially in the fight against rising antimicrobial resistance. Following the PRISMA 2020 guidelines, 16 peer-reviewed studies published from 2010 to 2024 and focusing on andrographolide's effects on bacteria, viruses, fungi, and protozoa were reviewed.
View Article and Find Full Text PDFAdvancing knowledge of One Health in China: lessons for One Health from China's dengue control and prevention programs.
Sci One Health
November 2024
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention, Chinese Center for Tropical Diseases Research, Shanghai 200025, China.
Background: The emergence of dengue fever has prompted significant public health responses, highlighting the need for a comprehensive understanding of One Health in addressing vector-borne diseases. China's experience in dengue control and prevention programs offers valuable insights into the successful integration of multidisciplinary strategies.
Aims: The review aims to: (1) systematically analyze lessons from China's dengue control and prevention programs, focusing on the integration of these efforts with the One Health approach; (2) underscore the reasons of optimizing the dengue control and prevention program; (3) highlight the alignment of China's dengue control strategies with the One Health framework; (4) contribute to global efforts in combating dengue, providing scientific evidence and strategic recommendations for other regions facing similar challenges.
Boosting the efficacy of fungal biocontrol: miRNA339-5p-mediated mosquito immunity regulation.
Pest Manag Sci
December 2024
State Key Laboratory of Green Pesticide, College of Plant Protection, South China Agricultural University, Guangzhou, China.
Article Synopsis
- Aedes mosquitoes spread serious diseases like dengue and zika, leading to a need for eco-friendly solutions due to insecticide resistance and few effective vaccines.
- This study explored the interaction between the fungus Metarhizium anisopliae and Aedes albopictus, finding that the fungal infection boosts the mosquitoes' immune response and activates specific immune genes that help fight off the fungus.
- Researchers discovered a microRNA called miR339-5p that regulates immune genes; using a synthetic version of this microRNA increased the fungus's effectiveness in killing mosquitoes, indicating a potential for genetic modifications to improve mosquito control methods.
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