Activity of microsomal hydroxylases was estimated by measuring the half-life of antipyrine secretion in healthy person saliva. Individual differences were found in the enzymatic activity. There main age groups exhibiting various activities of the microsomal enzymes were defined as follows: 1. 4-13 yrs -- high enzymatic activity; 2. 13-60 yrs -- stable activity; 3. older than 60 yrs -- decrease in the enzymatic activity. There were no sex variations in the microsomal enzymes activity.

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