During the period from 1971 to spring 1981, 85 patients with recent ruptures of the knee ligament were operated at the Hospital of Accident Surgery of Giessen. After 38.3 months on an average, 55 patients could be submitted to a follow-up examination. This examination comprised subjective troubles, clinical and X-ray examination of the injured knee joints. Above all, the full loading capacity of the operated extremity with a good mobility of the joint was evaluated. A good result was achieved in more than half of all cases. Only five patients showed an unsatisfactory results. A good result can only be achieved by an exact reconstruction of all injured structures carried out during the first few days following the accident. A later treatment of capsular ligament lesions will bring worse results.
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http://dx.doi.org/10.1007/BF02585678 | DOI Listing |
Shoulder Elbow
January 2025
Department of Orthopaedics, Northwestern Medicine, Warrenville, IL, USA.
Background: The treatment algorithm for traumatic shoulder instability has evolved, emphasizing the significance of glenoid bone loss and the glenoid track, addressing humeral, and glenoid vault bone deficiencies. This study examines trends and demographics of anterior shoulder instability procedures in the United States from 2010 to 2020.
Methods: PearlDiver database was queried for patients who underwent traumatic anterior shoulder instability procedures.
bioRxiv
January 2025
Institute for Systems Biology, Seattle, WA, USA.
Success of phage therapies is limited by bacterial defenses against phages. While a large variety of anti-phage defense mechanisms has been characterized, how expression of these systems is distributed across individual cells and how their combined activities translate into protection from phages has not been studied. Using bacterial single-cell RNA sequencing, we profiled the transcriptomes of ~50,000 cells from cultures of a human pathobiont, , infected with a lytic bacteriophage.
View Article and Find Full Text PDFJ Fr Ophtalmol
January 2025
Service d'ophtalmologie, centre hospitalier de Boulogne-sur-Mer, rue Jacques-Monod, 59000 Boulogne-sur-Mer, France. Electronic address:
Viruses
January 2025
State Research Center for Applied Microbiology and Biotechnology, City District Serpukhov, Moscow Region, 142279 Obolensk, Russia.
is a widely distributed nosocomial pathogen that causes various acute and chronic infections, particularly in immunocompromised patients. In this study, the activities of the K9-specific virulent phage AM24 and phage-encoded depolymerase DepAPK09 were assessed using in vivo mouse sepsis and burn skin infection models. In the mouse sepsis model, in the case of prevention or early treatment, a single K9-specific phage or recombinant depolymerase injection was able to protect 100% of the mice after parenteral infection with a lethal dose of of the K9-type, with complete eradication of the pathogen.
View Article and Find Full Text PDFMicroorganisms
January 2025
Emergency, Anesthesiological and Reanimation Sciences Department, Fondazione Policlinico Universitario A. Gemelli-IRCCS of Rome, 00168 Rome, Italy.
() is a Gram-negative, halophilic bacillus known for causing severe infections such as gastroenteritis, necrotizing fasciitis, and septic shock, with mortality rates exceeding 50% in high-risk individuals. Transmission occurs primarily through the consumption of contaminated seafood, exposure of open wounds to infected water, or, in rare cases, insect bites. The bacterium thrives in warm, brackish waters with high salinity levels, and its prevalence is rising due to the effects of climate change, including warming ocean temperatures and expanding coastal habitats.
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