AI Article Synopsis

  • Two groups of 20 subjects were exposed to altitudes of 3200 m and 3771 m for 10 days, experiencing rapid induction to high altitude.
  • A significant decrease in platelet counts was noted starting from day 2 at 3200 m and day 3 at 3771 m, with the counts remaining low throughout the study.
  • Initially, platelet aggregation was reduced at both altitudes, and while blood fibrinogen decreased on day 2 at 3771 m, it significantly increased by day 10 at both altitudes.

Article Abstract

Two groups of 20 subjects each were separately exposed to altitudes of 3200 m and 3771 m for 10 days by rapid induction requiring 14 and 16 hours respectively to reach high altitude camps. A statistically significant fall in platelet counts was observed from day 2 at 3200 m and day 3 at 3771 m and counts remained decreased. Platelet aggregation was also decreased initially at both altitudes. Blood fibrinogen decreased only on day 2 at 3771 m with a significant increase over control values by day 10 at both altitudes.

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Source
http://dx.doi.org/10.1016/0049-3848(82)90138-4DOI Listing

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