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Cohort retention in a pandemic response study: lessons from the SARS-CoV2 Immunity & Reinfection Evaluation (SIREN) study.
BMC Med Res Methodol
January 2025
United Kingdom Health Security Agency (UKHSA), London, UK.
Background: SIREN is a healthcare worker cohort study aiming to determine COVID-19 incidence, duration of immunity and vaccine effectiveness across 135 NHS organisations in four UK nations. Conducting an intensive prospective cohort study during a pandemic was challenging. We designed an evolving retention programme, informed by emerging evidence on best practice.
View Article and Find Full Text PDFThe essential role of magnesium in immunity and gut health: Impacts of dietary magnesium restriction on peritoneal cells and intestinal microbiome.
J Trace Elem Med Biol
January 2025
Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil. Electronic address:
Magnesium (Mg) is essential for life, and low levels impair immune function, promote chronic inflammation, and influence the intestinal microbiome, with the peritoneal cavity serving as a site for direct interaction between the cavity and intestinal contents, including the microbiota. This study investigates the effects of a Mg-restricted diet on peritoneal immune cells and its interplay with the intestinal microbiome. Male C57BL/6NTaq mice were divided into three groups: control, restricted, and restored.
View Article and Find Full Text PDFCommon issues of data science on the eco-environmental risks of emerging contaminants.
Environ Int
January 2025
Key Laboratory of Pollution Processes and Environmental Criteria (Ministry of Education), Carbon Neutrality Interdisciplinary Science Centre, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China.
Data-driven approaches (e.g., machine learning) are increasingly used to replace or assist laboratory studies in the study of emerging contaminants (ECs).
View Article and Find Full Text PDFFrom river to groundwater: Antibiotics pollution, resistance prevalence, and source tracking.
Environ Int
January 2025
School of Environment, South China Normal University, University Town, Guangzhou, China. Electronic address:
The extensive use of antibiotics has led to their frequent detection as residues in the environment. However, monitoring of their levels in groundwater and the associated ecological and health risks remains limited, and the impact of river pollution on groundwater is still unclear. This study focused on the highly urbanized Maozhou River and its groundwater.
View Article and Find Full Text PDFA solvent-free thermal desorption-gas chromatography-tandem mass spectrometry method (TD-GC-MS/MS) for the determination of polycyclic aromatic hydrocarbons in gas phase airborne samples.
J Chromatogr A
January 2025
Environmental Health Laboratory Branch, Center for Laboratory Sciences, California Department of Public Health, Richmond, CA 94804, USA.
A solvent-free, thermal extraction method for analysis of polycyclic aromatic hydrocarbons (PAHs) in gas phase airborne samples was developed. A fully automated thermal desorber (TD) coupled with highly selective and sensitive gas chromatography-tandem mass spectrometry (GC-MS/MS) was used to determine the concentration of trace level PAHs. Air sampling was conducted to tune the sampling and analytical conditions.
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