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Divergent responses of plant multi-element coupling to nitrogen and phosphorus addition in a meadow steppe.
BMC Plant Biol
January 2025
Institute of Grassland Science, School of Life Sciences, Key Laboratory of Vegetation Ecology, Ministry of Education, Northeast Normal University, Changchun, China.
The intricate biogeochemical cycling of multiple elements plays a pivotal role in upholding a myriad of ecosystem functions. However, our understanding of elemental stoichiometry and coupling in response to global changes remains primarily limited to plant carbon: nitrogen: phosphorus (C: N: P). Here, we assessed the responses of 11 elements in plants from different functional groups to global changes.
View Article and Find Full Text PDFFerroptosis triggers mitochondrial fragmentation via Drp1 activation.
Cell Death Dis
January 2025
CECAD Cluster of Excellence, University of Cologne, Cologne, Germany.
Constitutive mitochondrial dynamics ensure quality control and metabolic fitness of cells, and their dysregulation has been implicated in various human diseases. The large GTPase Dynamin-related protein 1 (Drp1) is intimately involved in mediating constitutive mitochondrial fission and has been implicated in mitochondrial cell death pathways. During ferroptosis, a recently identified type of regulated necrosis driven by excessive lipid peroxidation, mitochondrial fragmentation has been observed.
View Article and Find Full Text PDFBiomarkers and Social Determinants in atherosclerotic Arterial Diseases: A Scoping Review.
Ann Vasc Surg
January 2025
Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, 88100, Catanzaro, Italy; Interuniversity Center of Phlebolymphology (CIFL), "Magna Graecia" University, 88100 Catanzaro, Italy. Electronic address:
Background: Arterial diseases like coronary artery disease, carotid stenosis, peripheral artery disease, and abdominal aortic aneurysm have high morbidity and mortality, making them key research areas. Their multifactorial nature complicates patient treatment and prevention. Biomarkers offer insights into the biochemical and molecular processes, while social factors also significantly impact patients' health and quality of life.
View Article and Find Full Text PDFLeveraging Epigenetic Alterations in Pancreatic Ductal Adenocarcinoma for Clinical Applications.
Semin Cancer Biol
January 2025
Biomedical Research Center, Slovak Academy of Sciences, Dubravska Cesta 9, 84505 Bratislava, Slovakia. Electronic address:
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy characterized by late detection and poor prognosis. Recent research highlights the pivotal role of epigenetic alter- ations in driving PDAC development and progression. These changes, in conjunction with genetic mutations, contribute to the intricate molecular landscape of the disease.
View Article and Find Full Text PDFBiological studies reveal the role of trpA gene in biofilm formation, motility, hemolysis and virulence in Vibrio anguillarum.
Microb Pathog
January 2025
Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, International Research Center for Marine Biosciences at Shanghai Ocean University, Ministry of Science and Technology, National Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai 201306, China; Marine Biomedical Science and Technology Innovation Platform of Lin-gang Special Area, Shanghai 201306, China. Electronic address:
Vibrio anguillarum is a pathogen responsible for vibriosis in aquaculture animals. The formation of bacterial biofilm contributes to infections and increases resistance to antibiotics. Tryptophanase and its substrate tryptophan have been recognized as signal molecules regulating bacterial biofilm formation.
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