Reproductive fitness of carriers of heterochromatic variants of the human karyotype was found to be normal. The method was based on a comparison between known carriers and known non-carriers from the same pedigree in respect of live births, generation time and survival of offspring to reproductive age. A subset of the data had been included in an earlier study in which reproductive fitness of carriers was found to be significantly reduced. Our analysis suggests that the result may have been fortuitous, since it was not supported by the additional data. There was no evidence of heterogeneity between carriers of different types of variant or of different sex. There were indications of increased fetal losses to carriers, but the number of spontaneous abortions was insufficient to produce a detectable effect on gross reproductive fitness.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1399-0004.1982.tb00764.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Expression profile analysis of estrous-phased ovarian tissue of high and low prolific lines of inbred Swiss albino mice.
Mol Biol Rep
January 2025
Division of Animal Genetics, ICAR-Indian Veterinary Research Institute (ICAR-IVRI), Izatnagar, Bareilly 243 122, Uttar Pradesh, India.
Background: Litter size in mice is an important fitness and economic feature that is controlled by several genes and influenced by non-genetic factors too. High positive selection pressure in each generation for Litter size at birth (LSB), resulted in the development of high and low prolific lines of inbred Swiss albino mice (SAM). Despite uniform management conditions, these lines showed variability in LSB across the generation.
View Article and Find Full Text PDFFrequently arising ESX-1-associated phase variants influence fitness in the presence of host and antibiotic pressures.
mBio
January 2025
Department of Microbiology, UMass Chan Medical School, Worcester, Massachusetts, USA.
Unlabelled: (Mtb) exhibits an impressive ability to adapt to rapidly changing environments, despite its genome's apparent stability. Recently, phase variation through indel formation in homopolymeric tracts (HT) has emerged as a potentially important mechanism promoting adaptation in Mtb. This study examines the impact of common phase variants associated with the ESX-1 type VII secretion system, focusing on a highly variable HT upstream of the ESX-1 regulatory factor, .
View Article and Find Full Text PDFEcological and demographic drivers of kin-directed cooperation in a social bird: Insights from a long-term study.
J Anim Ecol
January 2025
Ecology & Evolutionary Biology, School of Biosciences, University of Sheffield, Sheffield, UK.
The evolution of sociality is one of the major evolutionary transitions in the history of life and a key step in this transition is the occurrence of kin associations. Yet, the question of what demographic processes and environmental factors generate kin-structured populations and drive kin-directed cooperation remains open. In this review, we synthesise 30 years of studies of the long-tailed tit Aegithalos caudatus, which has a kin-selected cooperative breeding system with redirected help: failed breeders may help to raise offspring of conspecifics, typically relatives, breeding nearby.
View Article and Find Full Text PDFMulti-source data recognition and fusion algorithm based on a two-layer genetic algorithm-back propagation model.
Front Big Data
January 2025
The College of Computer, Qinghai Normal University, Xining, China.
Traditional rainfall data collection mainly relies on rain buckets and meteorological data. It rarely considers the impact of sensor faults on measurement accuracy. To solve this problem, a two-layer genetic algorithm-backpropagation (GA-BP) model is proposed.
View Article and Find Full Text PDFCharacterization of resistance to Bacillus thuringiensis toxin Cry1Ac in Crocidosema sp. (Lepidoptera: Tortricidae) from Brazil.
Pest Manag Sci
January 2025
Department of Plant Protection, Federal University of Santa Maria, Santa Maria, Brazil.
Background: Crocidosema aporema (Walsingham 1914) has historically been the main bud borer species in soybean in Brazil; however, a recent study reported that this species is not C. aporema but an undescribed species. In recent seasons, injury by Crocidosema sp.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!