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Characteristics and predictors of outcome in children with severe acute bronchiolitis: A 10-yearexperience.

Arch Pediatr

October 2024

Department B, Bechir Hamza Children's Hospital of Tunis, Tunisia; Faculty of Medicine of Tunis, University El Manar, Tunis, Tunisia.

Article Synopsis
  • Severe acute bronchiolitis (SAB) is a serious illness in babies that can lead to long hospital stays or even death, making them need extra care in ICUs.
  • The study looked at 380 babies under 12 months old who were admitted to ICUs because of SAB, focusing on their health details and outcomes.
  • Key findings showed that younger babies and those with certain health issues were at higher risk for longer hospital stays or death, while a breathing support method called noninvasive ventilation (NIV) helped improve recovery.
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Objective: The objective of this study is to examine the risk factors associated with apnea in hospitalized patients diagnosed with bronchiolitis and to develop a nomogram prediction model for the early identification of patients who are at risk of developing apnea.

Methods: The clinical data of patients diagnosed with acute bronchiolitis and hospitalized at the Children's Hospital of Nanjing Medical University between February 2018 and May 2021 were retrospectively analyzed. LASSO regression and logistic regression analysis were used to determine the risk factors for apnea in these patients.

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Neonatal hypotonia presents with low muscle tone and an array of symptoms that vary depending on the etiology. The differential diagnosis for this condition is complex. It is crucial to exclude life-threatening causes before following a diagnostic algorithm and performing additional tests.

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Introduction Apnea is recognized as a serious and potentially life-threatening complication associated with Respiratory Syncope Virus (RSV). The literature reports a wide range of apnea rates for infants with comorbid factors. Prematurity and young chronological age have been historically associated with the risk of apnea in hospitalized infants.

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Introduction: High-flow nasal cannula (HFNC) is commonly used as first step respiratory support in infants with moderate-to-severe acute viral bronchiolitis (AVB). This device, however, fails to effectively manage respiratory distress in about a third of patients, and data are limited on determinants of patient response. The respiratory rate-oxygenation (ROX) index is a relevant tool to predict the risk for HFNC failure in adult patients with lower respiratory tract infections.

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