CNS injuries in brain contusions of a moderate and severe gravity leave lasting EEG traces that can be revealed on examining the patients in the state of sleep and drowsiness, and manifest in the form of pathological oscillations of the slow electrical processes in the second and decasecond intervals. These oscillations have an amplitude of 0.2 to 1.0 mV and more. In the course of brain function normalization the amplitude of the oscillations gradually decreases down to 0.05-0.15 mV. The pathological oscillations of the slow electrical processes in brain contusions are often more demonstrative than EEG changes.
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The coupling between dual-band or multi-band quasi-bound states in the continuum (q-BICs) is of great interest for their rich physics and promising applications. Here, we report tunable collective electromagnetic induced transparency-like (EIT-like) phenomenon due to coupling between dual-band collective electric dipolar and magnetic quadrupolar q-BICs, which are supported by an all-dielectric metasurface composed of periodic tilted silicon quadrumers. We show that this collective EIT-like phenomenon with a strong slow light effect can be realized by varying the nanodisk diameter or the tilt angle and that the transparency window wavelength, the quality factor, and the group index can all be tuned by changing the nanodisk size.
View Article and Find Full Text PDFJ Physiol
January 2025
Université Paris Cité, CNRS, Saints-Pères Paris Institute for the Neurosciences, Paris, France.
Fañanas cells (FCs) are cerebellar glia of unknown function. First described more than a century ago, they have been almost absent from the scientific literature ever since. Here, we combined whole-cell, patch clamp recordings, near-UV laser photolysis, dye-loading and confocal imaging for a first characterization of FCs in terms of their morphology, electrophysiology and glutamate-evoked currents.
View Article and Find Full Text PDFJ Prev Alzheimers Dis
February 2025
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA; Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA; School of Behavioral and Brain Sciences, University of Texas at Dallas, Dallas, TX, USA.
Background: Recent disease-modifying treatments for Alzheimer's disease show promise to slow cognitive decline, but show no efficacy towards reducing symptoms already manifested.
Objectives: To investigate the efficacy of a novel noninvasive brain stimulation technique in modulating cognitive functioning in Alzheimer's dementia (AD).
Design: Pilot, randomized, double-blind, parallel, sham-controlled study SETTING: Clinical research site at UT Southwestern Medical Center PARTICIPANTS: Twenty-five participants with clinical diagnoses of AD were enrolled from cognition specialty clinics.
Sensors (Basel)
January 2025
Department of Electrical Engineering and Information Technology, University of Naples Federico II, 80125 Naples, Italy.
Parkinson's disease (PD) is characterized by a slow, short-stepping, shuffling gait pattern caused by a combination of motor control limitations due to a reduction in dopaminergic neurons. Gait disorders are indicators of global health, cognitive status, and risk of falls and increase with disease progression. Therefore, the use of quantitative information on the gait mechanisms of PD patients is a promising approach, particularly for monitoring gait disorders and potentially informing therapeutic interventions, though it is not yet a well-established tool for early diagnosis or direct assessment of disease progression.
View Article and Find Full Text PDFMaterials (Basel)
January 2025
Federal Institute of Education, Science and Technology of Rio Grande do Norte (IFRN), São Gonçalo do Amarante 59291-727, Brazil.
The durability of reinforced concrete is associated with several factors that can trigger the corrosion of reinforcement bars. Among these factors, the most significant are chloride-ion attack and carbonation. This study evaluated, through accelerated testing, self-compacting concretes (SCCs) with reduced cement content in binary, ternary, and quaternary mixtures using high-early-strength Portland cement, fly ash (FA), metakaolin (MK), and hydrated lime (HL).
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