A study of the fine structure of cells obtained from the transformed cloned culture of strain L, that have developed from a single cell, demonstrated several different cell types. The clones contained both non-differentiated and poorly-differentiated cells. The presence of morphotypical signs in the poorly-differentiated cells allowed to reveal some cell clone types and the direction of their specialization process. The study confirms the idea on the presence of the stem cell elements in the transformed cell culture of strain L causing the heterogenous way of cytodifferentiation and determining the long-term stability of cell polymorphism in this cell strain.
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