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Value of bronchial amylase level for predicting ventilator associated pneumonia in intubated adults: a systematic review and meta-analysis.
BMC Pulm Med
November 2024
Department of Emergency, The First Affiliated Hospital of Zhejiang Chinese Medical University, Zhejiang Provincial Hospital of Traditional Chinese Medicine, Zhejiang, 310018, Hangzhou, China.
Article Synopsis
- This meta-analysis evaluated the effectiveness of bronchial amylase levels in predicting ventilator-associated pneumonia (VAP) in adults on ventilators, after analyzing data from multiple studies.
- A total of six studies involving 769 patients found that about 36% developed VAP, and the bronchial amylase levels varied widely.
- The findings suggested that while bronchial amylase has a useful role in VAP prediction (with a sensitivity of 78% and specificity of 75%), it should not be the sole determinant for diagnosis, and should be used alongside other clinical assessments.
Critical appraisal of how COVID-19 infection and imposed lockdowns have impacted gastroesophageal reflux: A review.
Medicine (Baltimore)
May 2024
Department of Basic Medical Science, Faculty of Medicine, Al-Balqa' Applied University, Al-Salt, Jordan.
Previous literature has demonstrated that COronaVIrus Disease of 2019 (COVID-19) impacts an individual gastrointestinal tract (GIT), causing symptoms like nausea, diarrhea, and loss of appetite. Severe acute respiratory syndrome coronavirus RNA has been discovered in the stool of infected individuals in earlier research. It was discovered that severe acute respiratory syndrome coronavirus was significantly expressed in the GIT, indicating that the virus can also infect the digestive system.
View Article and Find Full Text PDFComparison of the clinical characteristics in parents and their children in a series of family clustered Mycoplasma pneumoniae infections.
BMC Pulm Med
March 2024
Department of Respiratory and Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
Background: Mycoplasma pneumoniae infections have increased in China recently, causing some evidence of familial clustering. The purpose of this study was to compare the clinical features of parents and children in cases of familial clustering of Mycoplasma pneumoniae infection.
Methods: A retrospective analysis was performed on the cases of familial clustering of Mycoplasma pneumoniae infection, and the clinical characteristics of parents and children were compared.
Pulmonary Function Tests in Thunderstorm-associated Respiratory Symptoms: A Cross-sectional Study.
Iran J Med Sci
January 2024
Chronic Respiratory Diseases Research Center, Shahid Beheshti University of Medical Sciences,Tehran, Iran.
Background: Epidemic thunderstorm asthma is an observed increase in cases of acute bronchospasm following thunderstorms. This study aimed to compare the frequency of obstructive airway disease or bronchial hyperresponsiveness in subjects with thunderstorm-associated respiratory symptoms with subjects with similar symptoms presented at other times.
Methods: A cross-sectional study from June to November of 2013 was conducted on subjects with thunderstorm-associated respiratory symptoms living in Ahvaz City, Iran.
Aerobic glycolysis of bronchial epithelial cells rewires pneumonia and promotes bacterial elimination.
Infect Immun
February 2024
Department of Clinical Laboratory, The Affiliated Nanhua Hospital, Hengyang Medical College, University of South China, Hengyang, China.
The immune response to infection plays a key role in clinical symptoms. Previous investigations focused on the pro-inflammatory effects of leukocytes and the pivotal role of epithelial cell metabolic status in finely modulating the inflammatory response have been neglected. Herein, we examined how glycolysis in airway epithelial cells is affected by infection in an model.
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