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Deep Learning-Enabled Assessment of Right Ventricular Function Improves Prognostication After Transcatheter Edge-to-Edge Repair for Mitral Regurgitation.
Circ Cardiovasc Imaging
January 2025
DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance (M.L., A.H., E.R., M.v.S., A. Kastrati, H.S., M.J., E.X., K.-L.L., J.H., T.T.).
Background: Right ventricular (RV) function has a well-established prognostic role in patients with severe mitral regurgitation (MR) undergoing transcatheter edge-to-edge repair (TEER) and is typically assessed using echocardiography-measured tricuspid annular plane systolic excursion. Recently, a deep learning model has been proposed that accurately predicts RV ejection fraction (RVEF) from 2-dimensional echocardiographic videos, with similar diagnostic accuracy as 3-dimensional imaging. This study aimed to evaluate the prognostic value of the deep learning-predicted RVEF values in patients with severe MR undergoing TEER.
View Article and Find Full Text PDFCross-Sectional Association Between Left Ventricular Geometric Patterns, Cortical Cerebral Microinfarcts, and Cognition.
J Am Heart Assoc
January 2025
Background: Left ventricular (LV) geometric patterns are associated with cognitive impairment and cerebral small vessel disease. As a novel magnetic resonance imaging marker of cerebral small vessel disease and a risk factor for cognitive dysfunction, cortical cerebral microinfarcts (CMIs) have been associated with heart disease through mechanisms including cardioembolism and cerebral hypoperfusion. Further investigation is required to determine whether cortical CMIs could arise from hemodynamic changes related to LV geometry, thus elucidating the connection between LV geometry and cognitive function.
View Article and Find Full Text PDFInheritance of Imaging Parameters of Arrhythmic Risk in Mitral Valve Prolapse: A Pedigree Study.
Circ Cardiovasc Imaging
January 2025
Division of Cardiology, Department of Medicine, University of California, San Francisco (L.C., S.D., D.B., J.J.T., Q.F., L.T., A.H.R., R.J., S.H., H.H.H., Z.H.T., N.B.S., F.N.D.).
Background: A subset of patients with mitral valve prolapse (MVP), a highly heritable condition, experience sudden cardiac arrest (SCA) or sudden cardiac death (SCD). However, the inheritance of phenotypic imaging features of arrhythmic MVP remains unknown.
Methods: We recruited 23 MVP probands, including 9 with SCA/SCD and 14 with frequent/complex ventricular ectopy.
Left Atrial Strain in Omicron-Type COVID-19 Patients.
CJC Open
December 2024
Department of Cardiology, Tel Aviv Medical Center and School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Background: Information about left atrial (LA) 2-dimensional (2D) strain parameters in patients with the Omicron variant of COVID-19 is limited. The aim of this study is to evaluate LA strain (LAS) in COVID-19 patients with the Omicron variant and compare it to that of propensity-matched patients with the wild-type (WT) variant.
Methods: A total of 148 consecutive patients who were hospitalized with Omicron COVID-19 underwent an echocardiographic evaluation within the first day after hospital admission and were compared to propensity-matched patients (1:1) with the WT variant.
Accuracy of 2-dimensional speckle tracking echocardiography in diagnosis of coronary artery stenosis in stable angina pectoris.
Acta Cardiol
December 2024
Department of Cardiology, Fayoum University Hospital, Fayoum, Egypt.
Article Synopsis
- The study investigates the effectiveness of 2D speckle tracking echocardiography (2D-STE) in identifying significant coronary artery stenosis in patients with stable angina pectoris.
- Results indicate that patients with significant coronary artery disease (CAD) show lower global longitudinal strain (GLS) values, and 2D-STE demonstrates high sensitivity and specificity for detecting stenosis compared to standard echocardiography.
- The findings suggest that GLS and segmental longitudinal strain (SLS) provide a more accurate assessment of coronary artery health than conventional echocardiography, which relies on subjective evaluation of wall motion.
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