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Article Synopsis
  • The World Health Assembly set six global nutrition targets (GNTs) in 2012 to improve maternal and child health, but there has been no comprehensive report detailing progress from 2012 to 2021.
  • A study evaluated the prevalence and impact of these nutrition targets across 204 countries using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 and projected future trends up to 2050.
  • By 2021, only a few countries met some GNTs; most showed increased child overweight and notable decreases in female anaemia, highlighting a connection between societal development status and nutritional challenges.
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Congenital tremor (CT) caused by atypical porcine pestivirus (APPV) is a widespread disease in the swine industry. It is characterized by tremors in newborn piglets, but tremor description and association to other clinical signs are not well documented. This study's objectives were to characterize general and neurological clinical signs of APPV-induced CT and describe the progression and associations between the different signs.

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This case report underlines the diagnostic and therapeutic dilemmas in a 19-day-old neonate who had presented with features suggestive of chronic granulomatous disease (CGD). The baby had a history of fever, lethargy, and masses on the skin, for which an extensive diagnostic workup was needed to rule out infective etiology given no improvement with initial empiric therapy. Laboratory investigations, including imaging and genetic studies, confirmed the diagnosis of CGD.

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Biotinidase deficiency, a rare metabolic disorder characterised by abnormal biotin metabolism, affects the biotin-dependent carboxylase functions. Primarily characterised by neurological and skin disorder, it may present with myriad features. Early recognition is important for preventing long-term morbidities.

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Article Synopsis
  • Physiological regulatory issues in infants, like sleep and feeding problems, are linked to functional somatic symptoms (FSS) later on, especially in preadolescents.
  • The study utilized data from the Copenhagen Child Cohort, examining how early emotional and contact issues, alongside physiological problems, relate to FSS during pre- and late adolescence, controlling for maternal mental health and family challenges.
  • Results indicate that early physiological regulatory problems significantly predict FSS in preadolescents but have a weaker association in late adolescence, suggesting early intervention may help prevent long-term issues.
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