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Antimicrobial Susceptibility Testing-Guided Eradication Therapy in the Southeast Region of China: A Retrospective Study.
Infect Drug Resist
November 2024
Department of Gastroenterology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, People's Republic of China.
Background And Aim: Antibiotic resistance of is increasing worldwide, lowering its efficacy in eradication therapy and posing a serious threat to human health. This study evaluated resistance to antibiotics in the southeast region of China and explored factors related to eradication failure guided by antimicrobial susceptibility testing (AST).
Methods: In this retrospective study, patients who tested positive underwent gastroscopy, and infection was confirmed by histological staining and culture.
Infantile bacterial meningitis combined with sepsis caused by : A case report.
World J Clin Cases
November 2024
Department of Pediatrics, Mianyang Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Mianyang 621000, Sichuan Province, China.
Background: (SGSP) is a rare pathogen responsible for infant sepsis and meningitis and is potentially overlooked because it is not included in routine group B streptococcal screenings. Hence, we present a case of SGSP-induced infant meningitis and sepsis, accompanied by bronchopneumonia induced by multidrug-resistant (MRSA), providing insights into the identification, management, and prognosis of this bacterial infection.
Case Summary: A 45-day-old female infant presented with two episodes of high fever (maximum temperature: 39.
Clinical Impact of High-dose Esomeprazole-amoxicillin Dual Therapy as Rescue Treatment for Helicobacter pylori Infection : A Prospective, Multicenter, Randomized Trial.
J Clin Gastroenterol
December 2024
Department of Gastroenterology and Hepatology, Zhongshan Hospital (Xiamen), Fudan University.
Objective: This study aimed to compare the effectiveness and safety of high-dose dual therapy (HDDT) using esomeprazole and amoxicillin to furazolidone-based quadruple therapy (FBQT) in treating nonresponsive patients with Helicobacter pylori ( H. pylori ) infection.
Materials And Methods: A total of 209 patients with H.
Liposomal Drug Delivery against Using Furazolidone and N-Acetyl Cysteine in Augmented Therapy.
Pharmaceutics
August 2024
School of Pharmacy and Pharmaceutical Sciences, Faculty of Health Sciences and Wellbeing, University of Sunderland, Sunderland SR1 3SD, UK.
() infection is a significant global health concern, affecting approximately 50% of the world's population and leading to gastric ulcers, gastritis, and gastric cancer. The increase in antibiotic resistance has compromised the efficacy of existing therapeutic regimens, necessitating novel approaches for effective eradication. This study aimed to develop a targeted liposomal drug delivery system incorporating furazolidone and N-acetylcysteine (NAC) to enhance mucopenetration and improve eradication.
View Article and Find Full Text PDFGut microbiome and serum metabolome alterations associated with lactose intolerance (LI): a case‒control study and paired-sample study based on the American Gut Project (AGP).
mSystems
October 2024
Digestive Laboratory of Traditional Chinese Medicine, Research Institute of Spleen and Stomach Diseases, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Unlabelled: Lactose intolerance (LI) is a prevalent condition characterized by gastrointestinal symptoms that arise following lactose consumption. Recent evidence suggests that the gut microbiome may influence lactose levels in the gut. However, there is limited understanding regarding the alterations in microbiota and metabolism between individuals with LI and non-LI.
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